SLC9A3

Gene Symbol	SLC9A3
Entrez Gene	6550
Alt Symbol	NHE3
Species	Human
Gene Type	protein-coding
Description	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Other Description	NHE-3|Na(+)/H(+) exchanger 3|sodium/hydrogen exchanger 3|solute carrier family 9 (sodium/hydrogen exchanger)|solute carrier family 9 (sodium/hydrogen exchanger), member 3|solute carrier family 9 member 3
Swissprots	Q3MIW3 B7ZKR2 E9PF67 P48764
Accessions	AAM53435 EAW51006 EAW51007 P48764 BC011555 BC101669 AAI01670 BC101671 AAI01672 BC143328 AAI43329 BP270851 S83545 AAB50819 U28043 AAB48990 XM_011514095 XP_011512397 XM_011514096 XP_011512398 XM_011514097 XP_011512399 XM_011514098 XP_011512400 NM_001284351 NP_001271280 NM_004174 NP_004165
Function	Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Subcellular Location	Apical cell membrane {ECO:0000269|PubMed:19088451}; Multi-pass membrane protein {ECO:0000269|PubMed:19088451}. Note=In intestinal epithelial cells, localizes to the ileal brush border. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane.
Top Pathways	Proximal tubule bicarbonate reclamation, Protein digestion and absorption, Bile secretion, Mineral absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Sodium / Hydrogen Exchanger 3 protein fragment - ab114474 from Abcam Category Protein Source Wheat germ Species Human

SLC9A3 / NHE3 Antibody Blocking Peptide - LS-E16130 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NHE3/SLC9A3 Protein - H00006550-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SLC9A3 Blocking Peptide - 33R-1120 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC9A3 / NHE3 - H00006550-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SLC9A3 / NHE3 - H00006550-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Recombinant Human SLC9A3 - SLC9A3-31431TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Sodium/Hydrogen Exchanger 3 (NHE3) - RPE413Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

SLC9A3 Peptide, Human - M34GP14658H from Creative Peptides Category Peptide Source Synthetic. Species Human

NHE3/SLC9A3 Recombinant Protein Antigen - NBP1-82575PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NHE3/SLC9A3 Recombinant Protein Antigen - NBP1-82574PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Sodium/hydrogen exchanger 3 (SLC9A3), Recombinant Protein - MBS7075330 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell

Sodium/hydrogen exchanger 3 (SLC9A3), Recombinant Protein - MBS966425 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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