Gene Symbol |
ECD
|
Entrez Gene |
11319
|
Alt Symbol |
GCR2, HSGT1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ecdysoneless homolog (Drosophila)
|
Other Description |
protein SGT1|protein ecdysoneless homolog|suppressor of GCR2|suppressor of S. cerevisiae gcr2
|
Swissprots |
E9PAW8 C9JX46 O95905
|
Accessions |
EAW54477 EAW54478 O95905 AK022616 BAG51097 AK225519 AK315711 BC000721 AAH00721 BC103720 BM763002 CR457407 CAG33688 D88208 BAA75199 DA162516 DQ892172 ABM83098 DQ895366 ABM86292 NM_001135752 NP_001129224 NM_001135753 NP_001129225 NM_007265 NP_009196 NR_024203
|
Function |
Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes. {ECO:0000269|PubMed:16849563, ECO:0000269|PubMed:9928932}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16849563}. Nucleus {ECO:0000269|PubMed:16849563}.
|
Tissue Specificity |
Highly expressed in muscle and heart.
|