Gene Symbol | ECD |
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Entrez Gene | 11319 |
Alt Symbol | GCR2, HSGT1 |
Species | Human |
Gene Type | protein-coding |
Description | ecdysoneless homolog (Drosophila) |
Other Description | protein SGT1|protein ecdysoneless homolog|suppressor of GCR2|suppressor of S. cerevisiae gcr2 |
Swissprots | E9PAW8 C9JX46 O95905 |
Accessions | EAW54477 EAW54478 O95905 AK022616 BAG51097 AK225519 AK315711 BC000721 AAH00721 BC103720 BM763002 CR457407 CAG33688 D88208 BAA75199 DA162516 DQ892172 ABM83098 DQ895366 ABM86292 NM_001135752 NP_001129224 NM_001135753 NP_001129225 NM_007265 NP_009196 NR_024203 |
Function | Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes. {ECO:0000269|PubMed:16849563, ECO:0000269|PubMed:9928932}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16849563}. Nucleus {ECO:0000269|PubMed:16849563}. |
Tissue Specificity | Highly expressed in muscle and heart. |
HSGT1 CRISPR/Cas9 KO Plasmid (h) - sc-411601 from Santa Cruz Biotechnology
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HSGT1 HDR Plasmid (h) - sc-411601-HDR from Santa Cruz Biotechnology
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HSGT1 Double Nickase Plasmid (h) - sc-411601-NIC from Santa Cruz Biotechnology
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HSGT1 Double Nickase Plasmid (h2) - sc-411601-NIC-2 from Santa Cruz Biotechnology
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HSGT1 CRISPR Activation Plasmid (h) - sc-411601-ACT from Santa Cruz Biotechnology
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HSGT1 CRISPR Activation Plasmid (h2) - sc-411601-ACT-2 from Santa Cruz Biotechnology
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HSGT1 Lentiviral Activation Particles (h) - sc-411601-LAC from Santa Cruz Biotechnology
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HSGT1 Lentiviral Activation Particles (h2) - sc-411601-LAC-2 from Santa Cruz Biotechnology
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HSGT1 siRNA (h) - sc-90628 from Santa Cruz Biotechnology
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HSGT1 shRNA Plasmid (h) - sc-90628-SH from Santa Cruz Biotechnology
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HSGT1 shRNA (h) Lentiviral Particles - sc-90628-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU058221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7627 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7627 from Sigma-Aldrich
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ECD siRNA (Human) - CRH7749 from Cohesion Biosciences
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ECD - MBS8201897 from MyBioSource
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shRNA set against Human ECD (NM_007265.2) - SHH282833 from Creative biogene
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Human ECD siRNA - orb268251 from Biorbyt
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ECD shRNA Plasmid (Human) - CHH7749 from Cohesion Biosciences
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ECD miRNA 3'UTR clone - MiUTR3H-14702 from Creative biogene
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ECD miRNA 3'UTR clone - MiUTR3H-14703 from Creative biogene
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ECD miRNA 3'UTR clone - MiUTR3H-14704 from Creative biogene
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