HMGN3

Gene Symbol	HMGN3
Entrez Gene	9324
Alt Symbol	PNAS-24, PNAS-25, TRIP7
Species	Human
Gene Type	protein-coding
Description	high mobility group nucleosomal binding domain 3
Other Description	TR-interacting protein 7|high mobility group nucleosome-binding domain-containing protein 3|thyroid hormone receptor interacting protein 7
Swissprots	Q7RTT0 Q5HYD3 Q9BZT7 B2RD37 Q969M5 Q15651
Accessions	EAW48711 EAW48712 EAW48713 EAW48714 EAW48715 Q15651 AF274949 AAK07526 AF401520 AAK92012 AK124181 AK315391 BAG37784 AY043282 AAK85736 BC009529 AAH09529 BF790582 BI551210 BK000003 DAA00392 BK000006 DAA00395 BX648085 CAI46267 L40357 AAA73877 XM_005248768 XP_005248825 XM_005248769 XP_005248826 XM_006715604 XP_006715667 NM_001201362 NP_001188291 NM_001201363 NP_001188292 NM_004242 NP_004233 NM_138730 NP_620058
Function	Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus.
Tissue Specificity	Expressed in kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate and uterus. Low expression in liver, spleen, placenta and ovaries. {ECO:0000269|PubMed:11356838, ECO:0000269|PubMed:7776974}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HMGN3 full length protein - ab160428 from Abcam Category Protein Source Wheat germ Species Human

Human HMGN3 full length protein - ab183234 from Abcam Category Protein Source E. coli Species Human

HMGN3 Antibody Blocking Peptide - LS-E4486 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMGN3 Antibody Blocking Peptide - LS-E18511 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMGN3 Antibody Blocking Peptide - LS-E22620 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMGN3 Antibody Blocking Peptide - LS-E22621 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMGN3/TRIP7 Recombinant Protein - H00009324-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 10 ug 25 ug Species Human

HMGN3-Antibody-N-term-Blocking-Peptide - BP16805a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HMGN3 protein (His Tag) - orb139022 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

HMGN3 protein (His tag) - 80R-3929 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

HMGN3 / TRIP7 (1-77, His-tag) - AR51616PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

HMGN3 / TRIP7 (1-77, His-tag) - AR51616PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

HMGN3 / TRIP7 - H00009324-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

HMGN3 fusion protein - ag2692 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human HMGN3, His tagged - HMGN3-7380H from Creative Biomart Category Protein Source E. coli Species Human

Human HMGN3 Protein (His Tag) - 13914-H07E-20 from Sino Biological Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source E. coli Species Human

Recombinant Human High mobility group nucleosome-binding domain-containing prote - CSB-YP623009HU CSB-EP623009HU CSB-BP623009HU CSB-MP623009HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HMGN3, 1-77aa, Human, His tag, E.coli - ATGP2796 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

HMGN3 / TRIP7 (transcript variant 2) - TP302339 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

HMGN3 / TRIP7 (transcript variant 1) - TP313403 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human HMGN3 protein, MYC/DDK-tagged - HMGN3-524H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human HMGN3 protein, MYC/DDK-tagged - HMGN3-525H from Creative Biomart Category Protein Source HEK293 Species Human

HMGN3/TRIP7 Protein - NBP1-86904PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

HMGN3 Peptide, Human - M34GP07127H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human HMGN3/TRIP7 Protein - NBP2-51809 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 100 µg, 500 µg Source E.coli Species Human

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