SULF1

Gene Symbol SULF1
Entrez Gene 23213
Alt Symbol HSULF-1, SULF-1
Species Human
Gene Type protein-coding
Description sulfatase 1
Other Description extracellular sulfatase Sulf-1|sulfatase FP
Swissprots Q9UPS5 Q86YV8 Q8IWU6 Q8NCA2
Accessions EAW86953 EAW86954 EAW86955 Q8IWU6 AB029000 BAA83029 AF545571 AAO33315 AK055467 AK055607 AK074873 BAC11258 AK095341 AK123744 AK307951 AL136772 CAB66706 AY101175 AAM76860 BC012997 AAH12997 BC068565 AAH68565 BX571746 CAE11871 DA234578 DA726387 DA745191 EU831658 ACE87258 EU831741 ACE86575 XM_006716438 XP_006716501 XM_006716439 XP_006716502 XM_006716440 XP_006716503 XM_006716441 XP_006716504 XM_006716442 XP_006716505 XM_011517494 XP_011515796 XM_011517495 XP_011515797 XR_928764 NM_001128204 NP_001121676 NM_001128205 NP_001121677 NM_001128206 NP_001121678 NM_015170 NP_055985
Function Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation.
Subcellular Location Endoplasmic reticulum {ECO:0000250}. Golgi apparatus, Golgi stack {ECO:0000250}. Cell surface {ECO:0000250}. Note=Also localized on the cell surface. {ECO:0000250}.
Tissue Specificity Expressed at highest levels in testis, stomach, skeletal muscle, lung, kidney, pancreas, small intestine and colon. It is also detected in normal ovarian surface epithelial cells. Down-regulation seen in ovarian carcinoma cell lines, ovarian cancers, breast, pancreatic, renal and hepatocellular carcinoma cell lines.

Sulf-1 (H-81) - sc-98325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sulf-1 (H-81): sc-98325. Western blot analysis of Sulf-1 expression in non-transfected 293T: sc-117752 (A), human Sulf-1 transfected 293T: sc-177993 (B) and HeLa (C) whole cell lysates.

Sulf-1 (N-14) - sc-98153 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Sulfatase 1 antibody - ab168616 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Sulfatase 1 antibody (ab168616) at 1 µg/mlLane 1 : Sulfatase 1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-Sulfatase 1 antibody - ab172404 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Sulfatase 1 antibody (ab172404) at 1 µg/mlLane 1 : Sulfatase 1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L), peroxidase conjugated secondary antibody at 1/7500 dilution

Anti-Sulfatase 1 / SULF1 Antibody (aa609-871, Biotin) - LS-C298602 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Sulfatase 1 / SULF1 Antibody (aa609-871, FITC) - LS-C301896 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Sulfatase 1 / SULF1 Antibody (aa609-871) - LS-C296521 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant Sulfatase 1 / SULF1.

Anti-Sulfatase 1 / SULF1 Antibody (Internal) - LS-C112718 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
SULF1 antibody (1 ug/ml) staining of Human Testis lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Sulfatase 1 Antibody - NBP2-31584 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Sulfatase 1 Antibody (1A4) - H00023213-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1A4

Sulfatase 1 Antibody - NBP1-36992 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: Sulfatase 1 Antibody [NBP1-36992] - (1ug/ml) Analysis of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Sulfatase 1 Antibody - H00023213-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Sulfatase 1 Antibody [H00023213-B01P] - Analysis of SULF1 expression in transfected 293T cell line by SULF1 polyclonal antibody. Lane 1: SULF1 transfected lysate(95.81 KDa). Lane 2: Non-transfected lysate.

Sulfatase 1 Antibody - H00023213-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Sulfatase 1 Antibody [H00023213-D01P] - Analysis of SULF1 expression in transfected 293T cell line by SULF1 polyclonal antibody.Lane 1: SULF1 transfected lysate(101.00 KDa).Lane 2: Non-transfected lysate.

Monoclonal Anti-SULF1, (C-terminal) antibody produced in mouse - SAB1403129 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1A4
<B>Immunoblotting</B><BR/>Monoclonal Anti-SULF1: <B>Cat. No. SAB1403129</B>: Antibody concentration: 1 μg/mL. Specific band of ~36.2 kDa using immunogen protein lysate.

Anti-SULF1 antibody produced in rabbit - HPA054728 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SULF1: <B>Cat. No. HPA054728</B>: Immunohistochemical staining of Human colon shows moderate cytoplasmic and membranous positivity in glandular cells.

Anti-SULF1 antibody produced in goat - SAB2501219 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SULF1: <B>Cat. No. SAB2501219</B>: (1 μg/mL) staining of Human Testis lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SULF1-Antibody-internal-region - AF2920a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2920a (1 µg/ml) staining of Human Testis lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SULF1 antibody - orb101644 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of mouse heart (lane 1), rat pancreas (lane 2), mouse testis (lane 3), rat kidney(lane 4), rat small intestines (lane 5), rat ovary (lane 6) using SULF1 antibody (1 ug/ml)

SULF1 Antibody (OAEB01438) - OAEB01438 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Sulfatase 1 Antibody - abx101037 from Abbexa

Host Rabbit
Clonality Polyclonal

SULF1 antibody - AP16932PU-N from Acris Antibodies

Prices $310.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1µg/ml) staining of Human Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SULF1 antibody - H00023213-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of SULF1 expression in transfected 293T cell line (H00023213-T01) by SULF1 MaxPab polyclonal antibody. Lane 1: SULF1 transfected lysate(95.81 KDa). Lane 2: Non-transfected lysate.

SULF1 antibody - H00023213-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SULF1 antibody - H00023213-M01A from Acris Antibodies

Prices $360.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1A4

Anti-Sulfatase 1 Antibody - AC21-1823 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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