Gene Symbol | MYOCD |
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Entrez Gene | 93649 |
Alt Symbol | MYCD |
Species | Human |
Gene Type | protein-coding |
Description | myocardin |
Other Description | - |
Swissprots | Q8IZQ8 Q8N7Q1 Q5UBU5 |
Accessions | EAW89970 EAW89971 Q8IZQ8 AF532596 AAN33040 AK095846 AK096753 AK097821 BAC05177 AK128608 AK292885 BAF85574 AY764180 AAV33439 BC126307 AAI26308 BC143391 AAI43392 BQ000229 BX640673 CAE45805 DA650534 DB226467 XM_005256863 XP_005256920 XM_005256864 XP_005256921 NM_001146312 NP_001139784 NM_153604 NP_705832 NM_001146313 |
Function | Smooth muscle cells (SM) and cardiac muscle cells- specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis) (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in heart, aorta, and in smooth muscle cell-containing tissues: stomach, bladder, small intestine, colon, lung, placenta and uterus. Very faint expression in prostate and skeletal muscle. {ECO:0000269|PubMed:12640126, ECO:0000269|PubMed:20385216}. |
Myocardin CRISPR/Cas9 KO Plasmid (h) - sc-417707 from Santa Cruz Biotechnology
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Myocardin HDR Plasmid (h) - sc-417707-HDR from Santa Cruz Biotechnology
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Myocardin Double Nickase Plasmid (h) - sc-417707-NIC from Santa Cruz Biotechnology
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Myocardin Double Nickase Plasmid (h2) - sc-417707-NIC-2 from Santa Cruz Biotechnology
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Myocardin CRISPR Activation Plasmid (h) - sc-417707-ACT from Santa Cruz Biotechnology
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Myocardin CRISPR Activation Plasmid (h2) - sc-417707-ACT-2 from Santa Cruz Biotechnology
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Myocardin Lentiviral Activation Particles (h) - sc-417707-LAC from Santa Cruz Biotechnology
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Myocardin Lentiviral Activation Particles (h2) - sc-417707-LAC-2 from Santa Cruz Biotechnology
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Myocardin siRNA (h) - sc-43953 from Santa Cruz Biotechnology
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Myocardin shRNA Plasmid (h) - sc-43953-SH from Santa Cruz Biotechnology
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Myocardin shRNA (h) Lentiviral Particles - sc-43953-V from Santa Cruz Biotechnology
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Myocardin RNAi - H00093649-R01 from Novus Biologicals
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MISSION® esiRNA - EHU122771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14870 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14870 from Sigma-Aldrich
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MYOCD siRNA (Human) - CRJ4222 from Cohesion Biosciences
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shRNA set against Human MYOCD (NM_153604.2) - SHH348369 from Creative biogene
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Human Myocardin siRNA - orb274723 from Biorbyt
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MYOCD shRNA Plasmid (Human) - CHJ4222 from Cohesion Biosciences
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MYOCD miRNA 3'UTR clone - MiUTR3H-08237 from Creative biogene
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