| Gene Symbol | FXN |
|---|---|
| Entrez Gene | 505694 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | frataxin |
| Other Description | frataxin, mitochondrial |
| Swissprots | Q05B87 |
| Accessions | DAA26896 Q05B87 BC122620 AAI22621 NM_001080727 NP_001074196 |
| Function | Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. |
| Top Pathways | Porphyrin and chlorophyll metabolism |
frataxin, ELISA Kit - MBS9328729 from MyBioSource
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Bovine FXN ELISA Kit - E083593 from Biobool
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Frataxin, mitochondrial (FXN), ELISA Kit - MBS287210 from MyBioSource
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