ZYX

Gene Symbol	ZYX
Entrez Gene	7791
Alt Symbol	ESP-2, HED-2
Species	Human
Gene Type	protein-coding
Description	zyxin
Other Description	zyxin-2
Swissprots	A4D2G6 Q6I9S4 B4DQX7 Q15942
Accessions	AAS07459 CBX47470 CBX47471 EAL23788 EAW51848 EAW51849 EAW51850 EAW51851 Q15942 AK130138 AK298925 BAG61030 AK299005 BAG61089 AK302309 BAG63647 AK316227 BAH14598 BC002323 AAH02323 BC008743 AAH08743 BC009360 AAH09360 BC010031 AAH10031 BC017183 AAH17183 BU844538 CR457431 CAG33712 DQ892925 ABM83851 DQ896174 ABM87173 U15158 AAA78902 X94991 CAA64447 X95735 CAA65050 XM_011516567 XP_011514869 XM_011516568 XP_011514870 XM_011516569 XP_011514871 NM_001010972 NP_001010972 NM_003461 NP_003452
Function	Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Cell junction, focal adhesion. Note=Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1.
Top Pathways	Focal adhesion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Zyxin CRISPR/Cas9 KO Plasmid (h) - sc-402295 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin HDR Plasmid (h) - sc-402295-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin Double Nickase Plasmid (h) - sc-402295-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin Double Nickase Plasmid (h2) - sc-402295-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin CRISPR Activation Plasmid (h) - sc-402295-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin CRISPR Activation Plasmid (h2) - sc-402295-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin Lentiviral Activation Particles (h) - sc-402295-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin Lentiviral Activation Particles (h2) - sc-402295-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Zyxin siRNA (h) - sc-36370 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Zyxin shRNA Plasmid (h) - sc-36370-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Zyxin shRNA (h) Lentiviral Particles - sc-36370-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Zyxin RNAi - H00007791-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Zyxin RNAi - H00007791-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Zyxin RNAi - H00007791-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN23829 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23829 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ZYX siRNA (Human) - CRH5275 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ZYX - MBS8236975 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ZYX (NM_003461.4) - SHH456204 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ZYX(NM_001010972.1) - SHL163846 from Creative biogene Category siRNA Species Reactivities Human

Human ZYX siRNA - orb265777 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ZYX shRNA Plasmid (Human) - CHH5275 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ZYX miRNA 3'UTR clone - MiUTR1H-11777 from Creative biogene Species Reactivities Human

ZYX miRNA 3'UTR clone - MiUTR3H-04591 from Creative biogene Species Reactivities Human

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