Gene Symbol | CMIP |
---|---|
Entrez Gene | 80790 |
Alt Symbol | TCMIP |
Species | Human |
Gene Type | protein-coding |
Description | c-Maf inducing protein |
Other Description | C-Maf-inducing protein|tc-Mip |
Swissprots | Q8IY22 Q9C0G9 |
Accessions | EAW95527 EAW95528 EAW95529 Q8IY22 AB051481 BAB21785 AK096598 AK304418 BAH14178 AK308869 AY172689 AAO17720 BC038113 AAH38113 BM789770 CV570964 XM_005256179 XP_005256236 XM_005256181 XP_005256238 XM_005256182 XP_005256239 XM_011523352 XP_011521654 XM_011523353 XP_011521655 NM_030629 NP_085132 NM_198390 NP_938204 |
Function | Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor. {ECO:0000269|PubMed:12939343, ECO:0000269|PubMed:15128042}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Isoform 2 is translocated to the nucleus and is specifically recruited during minimal change nephrotic syndrome (MCNS). Detected in nuclear and cytoplasmic compartments during MCNS relapse. Expressed in cytoplasm only during MCNS remission and absent in normal patients. |
Tissue Specificity | Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturation and differentiation in thymus and fetal liver. {ECO:0000269|PubMed:12939343}. |
Human CMIP full length protein - ab164293 from Abcam
|
||||||||||
Recombinant Human CMIP Protein - H00080790-P01 from Novus Biologicals
|
||||||||||
CMIP - H00080790-P01-10 from Acris Antibodies
|
||||||||||
CMIP - H00080790-P01-25 from Acris Antibodies
|
||||||||||
CMIP fusion protein - ag17875 from Proteintech Group
|
||||||||||
CMIP fusion protein - ag3475 from Proteintech Group
|
||||||||||
Recombinant Human C-Maf-inducing protein(CMIP) - CSB-YP815577HU CSB-EP815577HU CSB-BP815577HU CSB-MP815577HU from Cusabio
|
||||||||||
C-Maf-inducing protein (CMIP), transcript variant C-mip. (transcript variant C-mip) - TP329369 from Acris Antibodies
|
||||||||||
C-Maf-inducing protein (CMIP), Recombinant Protein - MBS1432948 from MyBioSource
|
||||||||||
CMIP-Blocking-Peptide-C-term - BP20244b from Abgent, a WuXi AppTec company
|
||||||||||
CMIP Peptide, Human - M34GP03337H from Creative Peptides
|
||||||||||
CMIP Recombinant Protein Antigen - NBP2-58180PEP from Novus Biologicals
|
||||||||||
CMIP Recombinant Protein Antigen - NBP2-56410PEP from Novus Biologicals
|
||||||||||