Gene Symbol | CMIP |
---|---|
Entrez Gene | 80790 |
Alt Symbol | TCMIP |
Species | Human |
Gene Type | protein-coding |
Description | c-Maf inducing protein |
Other Description | C-Maf-inducing protein|tc-Mip |
Swissprots | Q8IY22 Q9C0G9 |
Accessions | EAW95527 EAW95528 EAW95529 Q8IY22 AB051481 BAB21785 AK096598 AK304418 BAH14178 AK308869 AY172689 AAO17720 BC038113 AAH38113 BM789770 CV570964 XM_005256179 XP_005256236 XM_005256181 XP_005256238 XM_005256182 XP_005256239 XM_011523352 XP_011521654 XM_011523353 XP_011521655 NM_030629 NP_085132 NM_198390 NP_938204 |
Function | Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor. {ECO:0000269|PubMed:12939343, ECO:0000269|PubMed:15128042}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Isoform 2 is translocated to the nucleus and is specifically recruited during minimal change nephrotic syndrome (MCNS). Detected in nuclear and cytoplasmic compartments during MCNS relapse. Expressed in cytoplasm only during MCNS remission and absent in normal patients. |
Tissue Specificity | Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturation and differentiation in thymus and fetal liver. {ECO:0000269|PubMed:12939343}. |
C-MIP CRISPR/Cas9 KO Plasmid (h) - sc-413403 from Santa Cruz Biotechnology
|
||||||||
C-MIP HDR Plasmid (h) - sc-413403-HDR from Santa Cruz Biotechnology
|
||||||||
C-MIP Double Nickase Plasmid (h) - sc-413403-NIC from Santa Cruz Biotechnology
|
||||||||
C-MIP Double Nickase Plasmid (h2) - sc-413403-NIC-2 from Santa Cruz Biotechnology
|
||||||||
C-MIP CRISPR Activation Plasmid (h) - sc-413403-ACT from Santa Cruz Biotechnology
|
||||||||
C-MIP CRISPR Activation Plasmid (h2) - sc-413403-ACT-2 from Santa Cruz Biotechnology
|
||||||||
C-MIP Lentiviral Activation Particles (h) - sc-413403-LAC from Santa Cruz Biotechnology
|
||||||||
C-MIP Lentiviral Activation Particles (h2) - sc-413403-LAC-2 from Santa Cruz Biotechnology
|
||||||||
C-MIP siRNA (h) - sc-93354 from Santa Cruz Biotechnology
|
||||||||
C-MIP shRNA Plasmid (h) - sc-93354-SH from Santa Cruz Biotechnology
|
||||||||
C-MIP shRNA (h) Lentiviral Particles - sc-93354-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU059291 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN6283 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6283 from Sigma-Aldrich
|
||||||||
CMIP siRNA (Human) - CRJ2917 from Cohesion Biosciences
|
||||||||
CMIP - MBS8210228 from MyBioSource
|
||||||||
shRNA set against Human CMIP (NM_030629.2) - SHH265893 from Creative biogene
|
||||||||
Human CMIP siRNA - orb273418 from Biorbyt
|
||||||||
CMIP shRNA Plasmid (Human) - CHJ2917 from Cohesion Biosciences
|
||||||||
CMIP miRNA 3'UTR clone - MiUTR3H-11037 from Creative biogene
|
||||||||
CMIP miRNA 3'UTR clone - MiUTR3H-11038 from Creative biogene
|