Gene Symbol |
SLC10A2
|
Entrez Gene |
6555
|
Alt Symbol |
ASBT, IBAT, ISBT, NTCP2, PBAM
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 10 (sodium/bile acid cotransporter), member 2
|
Other Description |
Na(+)-dependent ileal bile acid transporter|ileal apical sodium-dependent bile acid transporter|ileal sodium-dependent bile acid transporter|ileal sodium/bile acid cotransporter|sodium/taurocholate cotransporting polypeptide, ileal|solute carrier family 10 (sodium/bile acid cotransporter family), member 2
|
Swissprots |
A1L4F4 Q13839 Q12908
|
Accessions |
AAC95398 AAN16026 CAA91161 EAX09074 Q12908 BC130521 AAI30522 BC130523 AAI30524 HQ258177 ADR82931 U10417 AAC51870 NM_000452 NP_000443
|
Function |
Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Top Pathways |
Bile secretion
|