Gene Symbol | SLC10A2 |
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Entrez Gene | 6555 |
Alt Symbol | ASBT, IBAT, ISBT, NTCP2, PBAM |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
Other Description | Na(+)-dependent ileal bile acid transporter|ileal apical sodium-dependent bile acid transporter|ileal sodium-dependent bile acid transporter|ileal sodium/bile acid cotransporter|sodium/taurocholate cotransporting polypeptide, ileal|solute carrier family 10 (sodium/bile acid cotransporter family), member 2 |
Swissprots | A1L4F4 Q13839 Q12908 |
Accessions | AAC95398 AAN16026 CAA91161 EAX09074 Q12908 BC130521 AAI30522 BC130523 AAI30524 HQ258177 ADR82931 U10417 AAC51870 NM_000452 NP_000443 |
Function | Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | Bile secretion |
Asbt CRISPR/Cas9 KO Plasmid (h) - sc-402666 from Santa Cruz Biotechnology
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Asbt HDR Plasmid (h) - sc-402666-HDR from Santa Cruz Biotechnology
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Asbt Double Nickase Plasmid (h) - sc-402666-NIC from Santa Cruz Biotechnology
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Asbt Double Nickase Plasmid (h2) - sc-402666-NIC-2 from Santa Cruz Biotechnology
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Asbt CRISPR Activation Plasmid (h) - sc-402666-ACT from Santa Cruz Biotechnology
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Asbt CRISPR Activation Plasmid (h2) - sc-402666-ACT-2 from Santa Cruz Biotechnology
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Asbt Lentiviral Activation Particles (h) - sc-402666-LAC from Santa Cruz Biotechnology
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Asbt Lentiviral Activation Particles (h2) - sc-402666-LAC-2 from Santa Cruz Biotechnology
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Asbt siRNA (h) - sc-106906 from Santa Cruz Biotechnology
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Asbt shRNA Plasmid (h) - sc-106906-SH from Santa Cruz Biotechnology
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Asbt shRNA (h) Lentiviral Particles - sc-106906-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN1712 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1712 from Sigma-Aldrich
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SLC10A2 siRNA (Human) - CRH4445 from Cohesion Biosciences
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SLC10A2 RNAi - H00006555-R01 from Novus Biologicals
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SLC10A2 - MBS8218704 from MyBioSource
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shRNA set against Human SLC10A2 (NM_000452.2) - SHH408204 from Creative biogene
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Human SLC10A2 siRNA - orb264947 from Biorbyt
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SLC10A2 shRNA Plasmid (Human) - CHH4445 from Cohesion Biosciences
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