CH25H

Gene Symbol CH25H
Entrez Gene 9023
Alt Symbol C25H
Species Human
Gene Type protein-coding
Description cholesterol 25-hydroxylase
Other Description cholesterol 25-monooxygenase|h25OH
Swissprots B2RBY3 O95992
Accessions AAC97481 CAR81282 CBX84760 EAW50146 O95992 AF059214 AAC97483 AK314865 BAG37380 BC017843 AAH17843 BC072430 AAH72430 DQ892026 ABM82952 DQ895218 ABM86144 NM_003956 NP_003947
Function Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25- hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. {ECO:0000269|PubMed:9852097}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Primary bile acid biosynthesis

CH25H CRISPR/Cas9 KO Plasmid (h) - sc-402849 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H HDR Plasmid (h) - sc-402849-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H Double Nickase Plasmid (h) - sc-402849-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H Double Nickase Plasmid (h2) - sc-402849-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H CRISPR Activation Plasmid (h) - sc-402849-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H CRISPR Activation Plasmid (h2) - sc-402849-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H Lentiviral Activation Particles (h) - sc-402849-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H Lentiviral Activation Particles (h2) - sc-402849-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CH25H siRNA (h) - sc-90679 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CH25H shRNA Plasmid (h) - sc-90679-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CH25H shRNA (h) Lentiviral Particles - sc-90679-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CH25H RNAi - H00009023-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU053861 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6024 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6024 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04675 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04675

CH25H siRNA (Human) - CRH5950 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CH25H - MBS8205765 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CH25H (NM_003956.3) - SHH262617 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CH25H(NM_003956.3) - SHG173089 from Creative biogene

Category siRNA
Species Reactivities Human

Human CH25H siRNA - orb266452 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CH25H shRNA Plasmid (Human) - CHH5950 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CH25H miRNA 3'UTR clone - MiUTR1H-02089 from Creative biogene

Species Reactivities Human
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