SORBS1

Gene Symbol	SORBS1
Entrez Gene	10580
Alt Symbol	CAP, FLAF2, R85FL, SH3D5, SH3P12, SORB1
Species	Human
Gene Type	protein-coding
Description	sorbin and SH3 domain containing 1
Other Description	Fas-ligand associated factor 2|SH3 domain protein 5|c-Cbl associated protein|ponsin|sorbin and SH3 domain-containing protein 1
Swissprots	Q5T927 Q96KF3 Q5T928 Q9P2Q0 Q5T931 A6NID8 Q9BX64 Q8IVK0 Q96KF4 Q9UHN7 Q5T924 Q5T923 Q5T930 Q9Y338 Q9BX66 D3DR42 Q9BX65 A6NEK3 Q9UFT2 A6NJS4 A7MD40 O43857 A0AED4 Q5T929 Q5T932 Q7LBE5 Q8IVQ4
Accessions	EAW49998 EAW49999 EAW50000 EAW50001 EAW50002 EAW50003 EAW50004 EAW50005 EAW50006 EAW50007 EAW50008 Q9BX66 AB037717 BAA92534 AF136380 AAD27647 AF136381 AAF22175 AF330623 AAK57479 AF330624 AAK57480 AF356525 AAK37563 AF356526 AAK37564 AF356527 AAK37565 AJ489942 CAD34588 AK022468 AK294924 BAG58006 AK300407 BAG62137 AK304130 BAG65026 AK304753 BAH14253 AL117472 CAB55947 AL122082 AL707894 AL832353 AM260536 CAJ97431 AM393082 CAL37960 BC042612 AAH42612 BC152463 AAI52464 BC160134 AAI60134 BX640814 CAE45892 DC334283 U70668 AAB93496 XM_006717570 XP_006717633 XM_006717574 XP_006717637 XM_006717581 XP_006717644 XM_006717582 XP_006717645 XM_006717585 XP_006717648 XM_006717586 XP_006717649 XM_006717589 XP_006717652 XM_006717590 XP_006717653 XM_006717591 XP_006717654 XM_006717593 XP_006717656 XM_006717594 XP_006717657 XM_006717595 XP_006717658 XM_011539136 XP_011537438 XM_011539137 XP_011537439 XM_011539138 XP_011537440 XM_011539139 XP_011537441 XM_011539140 XP_011537442 XM_011539141 XP_011537443 XM_011539142 XP_011537444 XM_011539143 XP_011537445 XM_011539144 XP_011537446 XM_011539145 XP_011537447 XM_011539146 XP_011537448 XM_011539147 XP_011537449 XM_011539148 XP_011537450 XM_011539149 XP_011537451 XM_011539150 XP_011537452 XM_011539151 XP_011537453 XM_011539152 XP_011537454 XM_011539153 XP_011537455 XM_011539154 XP_011537456 XM_011539155 XP_011537457 XM_011539156 XP_011537458 XM_011539157 XP_011537459 XM_011539158 XP_011537460 XM_011539159 XP_011537461 XM_011539160 XP_011537462 XM_011539161 XP_011537463 XM_011539162 XP_011537464 XM_011539163 XP_011537465 XM_011539164 XP_011537466 XM_011539165 XP_011537467 XM_011539166 XP_011537468 XM_011539167 XP_011537469 XM_011539168 XP_011537470 XM_011539169 XP_011537471 NM_001034954 NP_001030126 NM_001034955 NP_001030127 NM_001034956 NP_001030128 NM_001034957 NP_001030129 NM_001290294 NP_001277223 NM_001290295 NP_001277224 NM_001290296 NP_001277225 NM_001290297 NP_001277226 NM_001290298 NP_001277227 NM_006434 NP_006425 NM_015385 NP_056200 NM_024991 NP_079267
Function	Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin- stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity). {ECO:0000250|UniProtKB:Q62417}.
Subcellular Location	Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus {ECO:0000250}. Nucleus matrix {ECO:0000250}. Note=Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation. {ECO:0000250}.
Tissue Specificity	Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:11374898, ECO:0000269|PubMed:17462669}.
Top Pathways	Adherens junction, Insulin signaling pathway, PPAR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SORBS1 peptide - ab18388 from Abcam Category Peptide Source CHO Species Human

SORBS1 / Ponsin Antibody Blocking Peptide - LS-E410 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SORBS1 / Ponsin Antibody Blocking Peptide - LS-E25367 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SORBS1 / Ponsin Antibody Blocking Peptide - LS-E26293 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SORBS1 / Ponsin Antibody Blocking Peptide - LS-E26063 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SORBS1 / Ponsin Antibody Blocking Peptide - LS-E18593 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SORBS1-Antibody-Center-Blocking-peptide - BP10689c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SORBS1 (C Terminus) blocking peptide - GTX24551-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Pig, Rat

SORBS1 (internal region) blocking peptide - GTX89074-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

SORBS1 (internal) blocking peptide - GTX89384-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SORBS1 Immunizing peptide - orb16739 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

SORBS1 Peptide - AC21-0195-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SORBS1 Peptide - AC21-0891-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SORBS1 Peptide - AC21-1125-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SORBS1 Peptide - 46-415P from ProSci Category Peptide

SORBS1 Peptide - 46-416P from ProSci Category Peptide

SORBS1 Peptide - 46-414P from ProSci Category Peptide Species Human

SORBS1 fusion protein - ag4889 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SORBS1 fusion protein - Ag4828 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Sorbin and SH3 domain-containing protein 1(SORBS1) ,partial - CSB-YP883617HU CSB-EP883617HU CSB-BP883617HU CSB-MP883617HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SORBS1 / Ponsin (transcript variant 4) - TP324759 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SORBS1/ponsin, Peptide - MBS425729 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

SORBS1/Ponsin, Peptide - MBS428597 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Pig

SORBS1/ponsin, Peptide - MBS428526 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

SORBS1 Recombinant Protein Antigen - NBP2-33383PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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