| Gene Symbol |
MAN1A2
|
| Entrez Gene |
10905
|
| Alt Symbol |
MAN1B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mannosidase, alpha, class 1A, member 2
|
| Other Description |
alpha-1,2-mannosidase IB|alpha1,2-mannosidase|mannosyl-oligosaccharide 1,2-alpha-mannosidase IB|processing alpha-1,2-mannosidase IB
|
| Swissprots |
Q9H510 O60476
|
| Accessions |
AAC26200 AAC26201 EAW56675 EAW56676 O60476 AF027156 AAC26169 AK001970 BAG50997 AK090840 AK098129 AK307842 AU133800 BC015874 BC052954 BC063300 AAH63300 XM_006710302 XP_006710365 XM_011540536 XP_011538838 XR_946528 NM_006699 NP_006690
|
| Function |
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
|
| Subcellular Location |
Golgi apparatus membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Highest levels of expression in placenta and testis.
|
| Top Pathways |
N-Glycan biosynthesis, Protein processing in endoplasmic reticulum
|