Gene Symbol | MAN1A2 |
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Entrez Gene | 10905 |
Alt Symbol | MAN1B |
Species | Human |
Gene Type | protein-coding |
Description | mannosidase, alpha, class 1A, member 2 |
Other Description | alpha-1,2-mannosidase IB|alpha1,2-mannosidase|mannosyl-oligosaccharide 1,2-alpha-mannosidase IB|processing alpha-1,2-mannosidase IB |
Swissprots | Q9H510 O60476 |
Accessions | AAC26200 AAC26201 EAW56675 EAW56676 O60476 AF027156 AAC26169 AK001970 BAG50997 AK090840 AK098129 AK307842 AU133800 BC015874 BC052954 BC063300 AAH63300 XM_006710302 XP_006710365 XM_011540536 XP_011538838 XR_946528 NM_006699 NP_006690 |
Function | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
Tissue Specificity | Highest levels of expression in placenta and testis. |
Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |
MAN1A2 CRISPR/Cas9 KO Plasmid (h) - sc-411536 from Santa Cruz Biotechnology
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MAN1A2 HDR Plasmid (h) - sc-411536-HDR from Santa Cruz Biotechnology
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MAN1A2 Double Nickase Plasmid (h) - sc-411536-NIC from Santa Cruz Biotechnology
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MAN1A2 Double Nickase Plasmid (h2) - sc-411536-NIC-2 from Santa Cruz Biotechnology
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MAN1A2 CRISPR Activation Plasmid (h) - sc-411536-ACT from Santa Cruz Biotechnology
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MAN1A2 CRISPR Activation Plasmid (h2) - sc-411536-ACT-2 from Santa Cruz Biotechnology
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MAN1A2 Lentiviral Activation Particles (h) - sc-411536-LAC from Santa Cruz Biotechnology
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MAN1A2 Lentiviral Activation Particles (h2) - sc-411536-LAC-2 from Santa Cruz Biotechnology
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MAN1A2 siRNA (h) - sc-88443 from Santa Cruz Biotechnology
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MAN1A2 shRNA Plasmid (h) - sc-88443-SH from Santa Cruz Biotechnology
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MAN1A2 shRNA (h) Lentiviral Particles - sc-88443-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU098801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12962 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12962 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11801 from Sigma-Aldrich
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MAN1A2 siRNA (Human) - CRH7434 from Cohesion Biosciences
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MAN1A2 RNAi - H00010905-R01 from Novus Biologicals
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shRNA set against Human Man1a (NM_006699.3) - SHH337243 from Creative biogene
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shRNA set against Human MAN1A2(NM_006699.3) - SHH172379 from Creative biogene
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Human MAN1A2 siRNA - orb267936 from Biorbyt
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MAN1A2 shRNA Plasmid (Human) - CHH7434 from Cohesion Biosciences
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MAN1A2 miRNA 3'UTR clone - MiUTR1H-06034 from Creative biogene
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