Gene Symbol | GNA11 |
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Entrez Gene | 2767 |
Alt Symbol | FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2 |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
Other Description | G-protein subunit alpha-11|g alpha-11|guanine nucleotide-binding protein G(y) subunit alpha|guanine nucleotide-binding protein subunit alpha-11 |
Swissprots | P29992 O15109 Q14350 Q6IB00 |
Accessions | AAC25615 EAW69339 EAW69340 P29992 AB209435 BAD92672 AF011497 AAB64303 AF493900 AAM12614 AK091639 AL110227 CAH56407 BC001528 BC051315 BC063426 BC089041 AAH89041 BC096225 AAH96225 BC096226 AAH96226 BC096227 AAH96227 BC111027 CR457004 CAG33285 HY118575 L40630 AAA99949 M69013 AAA58624 NM_002067 NP_002058 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C. |
Subcellular Location | Cell membrane {ECO:0000305|PubMed:18703424}; Lipid-anchor {ECO:0000305|PubMed:18703424}. Cytoplasm {ECO:0000269|PubMed:18703424}. Note=In testicular cells, expressed exclusively in the cytoplasm. |
Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:18703424}. |
Top Pathways | Gap junction, Vascular smooth muscle contraction, Chagas disease (American trypanosomiasis), Amoebiasis, Calcium signaling pathway |
G α 11 (D-6) - sc-390382 from Santa Cruz Biotechnology
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G α 11 (D-17) - sc-394 from Santa Cruz Biotechnology
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G α 11 (T-16) - sc-26792 from Santa Cruz Biotechnology
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G α i/o/t/z (D-15) - sc-12798 from Santa Cruz Biotechnology
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G α q/11 (C-16) - sc-46972 from Santa Cruz Biotechnology
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G α q/11 (K-18) - sc-46974 from Santa Cruz Biotechnology
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G α q/11/14 (H-300) - sc-28587 from Santa Cruz Biotechnology
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Anti-GNA11 antibody - ab192507 from Abcam
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Anti-GNA11 antibody - ab130980 from Abcam
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Anti-GNA11 Antibody - LS-C332227 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa193-242) - LS-C151857 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30, FITC) - LS-C235756 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30, AP) - LS-C235757 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30, PE) - LS-C235759 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30, Biotin) - LS-C246706 from LifeSpan Bioscience
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Anti-GNA11 Antibody - LS-C310509 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30, APC) - LS-C246705 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30, Azide-free, HRP) - LS-C249082 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30) - LS-C321671 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa61-110) - LS-C151858 from LifeSpan Bioscience
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Anti-GNA11 Antibody - LS-C341479 from LifeSpan Bioscience
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Anti-GNA11 Antibody (aa1-30) - LS-C157778 from LifeSpan Bioscience
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GNA11 Antibody - NBP2-16697 from Novus Biologicals
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GNA11 Antibody - NBP1-98606 from Novus Biologicals
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GNA11 Antibody - NBP1-98590 from Novus Biologicals
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