| Gene Symbol | GNA11 |
|---|---|
| Entrez Gene | 2767 |
| Alt Symbol | FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| Other Description | G-protein subunit alpha-11|g alpha-11|guanine nucleotide-binding protein G(y) subunit alpha|guanine nucleotide-binding protein subunit alpha-11 |
| Swissprots | P29992 O15109 Q14350 Q6IB00 |
| Accessions | AAC25615 EAW69339 EAW69340 P29992 AB209435 BAD92672 AF011497 AAB64303 AF493900 AAM12614 AK091639 AL110227 CAH56407 BC001528 BC051315 BC063426 BC089041 AAH89041 BC096225 AAH96225 BC096226 AAH96226 BC096227 AAH96227 BC111027 CR457004 CAG33285 HY118575 L40630 AAA99949 M69013 AAA58624 NM_002067 NP_002058 |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C. |
| Subcellular Location | Cell membrane {ECO:0000305|PubMed:18703424}; Lipid-anchor {ECO:0000305|PubMed:18703424}. Cytoplasm {ECO:0000269|PubMed:18703424}. Note=In testicular cells, expressed exclusively in the cytoplasm. |
| Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:18703424}. |
| Top Pathways | Gap junction, Vascular smooth muscle contraction, Chagas disease (American trypanosomiasis), Amoebiasis, Calcium signaling pathway |