ddb2

Gene Symbol ddb2
Entrez Gene 100004133
Alt Symbol si:dkey-45f10.3
Species Zebrafish
Gene Type protein-coding
Description damage-specific DNA binding protein 2
Other Description DNA damage-binding protein 2|damage-specific DNA-binding protein 2
Swissprots Q2YDS1 Q1LUF7 Q1LUF8
Accessions Q2YDS1 BC110096 AAI10097 XM_005159034 XP_005159091 XM_005159035 XP_005159092 NM_001083061 NP_001076530
Function Required for DNA repair. Binds to ddb1 to form the UV- damaged DNA-binding protein complex (the UV-DDB complex). The UV- DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. Also appears to function as the substrate recognition module for a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex which may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways Nucleotide excision repair, p53 signaling pathway, Ubiquitin mediated proteolysis

Recombinant Zebrafish DDB2 - DDB2-5371Z from Creative Biomart

Category Protein
Source Mammalian Cells
Species Zebrafish

Recombinant Danio rerio DNA damage-binding protein 2(ddb2) - CSB-YP652125DIL CSB-EP652125DIL CSB-BP652125DIL CSB-MP652125DIL from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Zebrafish

DNA damage-binding protein 2 (ddb2), Recombinant Protein - MBS1296286 from MyBioSource

Category Protein
Prices $1,280.00, $1,280.00, $1,500.00, $1,500.00, $2,105.00, $2,105.00, $2,570.00, $2,570.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Zebrafish
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