| Gene Symbol |
Rxfp1
|
| Entrez Gene |
381489
|
| Alt Symbol |
Gm1018, Lgr7
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
relaxin/insulin-like family peptide receptor 1
|
| Other Description |
leucine-rich repeat-containing 7|leucine-rich repeat-containing G protein-coupled receptor 7|leucine-rich repeat-containing G-protein coupled receptor 7|relaxin family peptide receptor 1|relaxin receptor 1
|
| Swissprots |
Q6R6I7 Q80UD3
|
| Accessions |
EDL15456 EDL15457 EDL15458 Q6R6I7 AK054129 AK086423 AK137655 AK142756 AY255542 AAO85054 AY509975 AAR97515 BC156370 AAI56371 BC172664 AAI72664 XM_006501629 XP_006501692 XM_006501630 XP_006501693 XR_375538 NM_212452 NP_997617
|
| Function |
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. {ECO:0000269|PubMed:15566402}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|