Gene Symbol | Rxfp1 |
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Entrez Gene | 381489 |
Alt Symbol | Gm1018, Lgr7 |
Species | Mouse |
Gene Type | protein-coding |
Description | relaxin/insulin-like family peptide receptor 1 |
Other Description | leucine-rich repeat-containing 7|leucine-rich repeat-containing G protein-coupled receptor 7|leucine-rich repeat-containing G-protein coupled receptor 7|relaxin family peptide receptor 1|relaxin receptor 1 |
Swissprots | Q6R6I7 Q80UD3 |
Accessions | EDL15456 EDL15457 EDL15458 Q6R6I7 AK054129 AK086423 AK137655 AK142756 AY255542 AAO85054 AY509975 AAR97515 BC156370 AAI56371 BC172664 AAI72664 XM_006501629 XP_006501692 XM_006501630 XP_006501693 XR_375538 NM_212452 NP_997617 |
Function | Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. {ECO:0000269|PubMed:15566402}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
Relaxin Receptor 1 CRISPR/Cas9 KO Plasmid (m) - sc-436294 from Santa Cruz Biotechnology
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Relaxin Receptor 1 HDR Plasmid (m) - sc-436294-HDR from Santa Cruz Biotechnology
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Relaxin Receptor 1 Double Nickase Plasmid (m) - sc-436294-NIC from Santa Cruz Biotechnology
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Relaxin Receptor 1 Double Nickase Plasmid (m2) - sc-436294-NIC-2 from Santa Cruz Biotechnology
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Relaxin Receptor 1 CRISPR Activation Plasmid (m) - sc-436294-ACT from Santa Cruz Biotechnology
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Relaxin Receptor 1 CRISPR Activation Plasmid (m2) - sc-436294-ACT-2 from Santa Cruz Biotechnology
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Relaxin Receptor 1 Lentiviral Activation Particles (m) - sc-436294-LAC from Santa Cruz Biotechnology
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Relaxin Receptor 1 Lentiviral Activation Particles (m2) - sc-436294-LAC-2 from Santa Cruz Biotechnology
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Relaxin Receptor 1 siRNA (m) - sc-40178 from Santa Cruz Biotechnology
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Relaxin Receptor 1 shRNA Plasmid (m) - sc-40178-SH from Santa Cruz Biotechnology
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Relaxin Receptor 1 shRNA (m) Lentiviral Particles - sc-40178-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN40631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40631 from Sigma-Aldrich
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RXFP1 siRNA (Mouse) - CRN4860 from Cohesion Biosciences
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RXFP1 - MBS8209568 from MyBioSource
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shRNA set against Mouse RXFP1 (NM_212452.1) - SHH400932 from Creative biogene
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shRNA set against Mouse Rxfp1(NM_212452.1) - SHR191262 from Creative biogene
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RXFP1 shRNA Plasmid (Mouse) - CHN4860 from Cohesion Biosciences
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RXFP1 miRNA 3'UTR clone - MiUTR1M-10351 from Creative biogene
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