Gene Symbol | ADIPOR2 |
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Entrez Gene | 79602 |
Alt Symbol | ACDCR2, PAQR2 |
Species | Human |
Gene Type | protein-coding |
Description | adiponectin receptor 2 |
Other Description | adiponectin receptor protein 2|progestin and adipoQ receptor family member II |
Swissprots | Q53YY5 Q86V24 Q9H737 |
Accessions | CBS99527 EAW88924 Q86V24 AK025085 BAB15062 AK127196 BAC86881 AK128511 BAC87473 AY424280 AAR08368 BC004906 BC051858 AAH51858 BM973815 HQ448616 ADQ33094 XM_005253789 XP_005253846 XM_006719018 XP_006719081 XM_011521024 XP_011519326 XM_011521025 XP_011519327 NM_024551 NP_078827 |
Function | Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin. {ECO:0000269|PubMed:12802337}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:12802337}; Multi-pass membrane protein {ECO:0000269|PubMed:12802337}. Note=Localized to the cell membrane and intracellular organelles. |
Tissue Specificity | Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung. {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:16044242}. |
Top Pathways | Adipocytokine signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway |
Human Adiponectin Receptor 2 full length protein - ab153509 from Abcam
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ADIPOR2 Blocking Peptide - LS-E7738 from LifeSpan Bioscience
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AdipoR2 Recombinant Protein - H00079602-P01 from Novus Biologicals
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ADIPOR2-Antibody-Center-Blocking-Peptide - BP5105c from Abgent, a WuXi AppTec company
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Adiponectin Receptor 2 peptide - orb108417 from Biorbyt
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ADIPOR2 Blocking Peptide - 33R-1540 from Fitzgerald
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Human Adiponectin Receptor 2 Protein - abx065173 from Abbexa
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Adiponectin Receptor 2 - H00079602-P01 from Acris Antibodies
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Adiponectin Receptor 2 - AP05204CP-N from Acris Antibodies
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Adiponectin Receptor 2 (ADIPOR2), Human - 20-6317 from ARP American Research Products
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ADIPOR2 fusion protein - Ag5744 from Proteintech Group
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Recombinant Human ADIPOR2, GST-tagged - ADIPOR2-9427H from Creative Biomart
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Recombinant Human ADIPOR2, GST-tagged - ADIPOR2-210H from Creative Biomart
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Recombinant Human ADIPOR2, His-tagged, GST-tagged - ADIPOR2-3200H from Creative Biomart
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Recombinant Adiponectin Receptor 2 (ADIPOR2) - RPA132Hu01 from Uscn Life Science Inc.
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Recombinant Adiponectin Receptor 2 (ADIPOR2) - RPA132Hu02 from Uscn Life Science Inc.
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Recombinant Adiponectin Receptor 2 (ADIPOR2) - RPA132Ra01 from Uscn Life Science Inc.
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Recombinant Adiponectin Receptor 2 (ADIPOR2) - RPA132Hu01 from Cloud-clone
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Recombinant Adiponectin Receptor 2 (ADIPOR2) - RPA132Hu02 from Cloud-clone
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ADIPOR2 Peptide (OEEG01136) - OEEG01136 from Aviva Systems Biology
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Adiponectin Receptor 2 (ADIPOR2) - RPU140114 from Biomatik
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Adiponectin, globular domain, Canine - MBS2010670 from MyBioSource
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Adiponectin Receptor 2 Protein (Recombinant) - abx168257 from Abbexa
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Adiponectin Receptor 2, Peptide - MBS396412 from MyBioSource
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AdipoR2 Recombinant Protein Antigen - NBP1-91652PEP from Novus Biologicals
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