GDF6

Gene Symbol GDF6
Entrez Gene 392255
Alt Symbol BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1
Species Human
Gene Type protein-coding
Description growth differentiation factor 6
Other Description GDF-6|Klip-Feil malformation|Klippel-Feil malformation|Klippel-Feil syndrome|bone morphogenetic protein 13|growth/differentiation factor 16|growth/differentiation factor 6
Swissprots Q6PI58 Q6KF10
Accessions AGF34263 AGF34264 EAW91747 Q6KF10 AJ537424 CAD60934 BC043222 AAH43222 BC127947 AAI27948 BC127948 AAI27949 BC156445 AAI56446 XM_011517030 XP_011515332 NM_001001557 NP_001001557
Function Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. May signal through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A. {ECO:0000269|PubMed:23307924}.
Subcellular Location Secreted {ECO:0000269|PubMed:23307924}.
Top Pathways TGF-beta signaling pathway, Hippo signaling pathway

GDF-6 (N-19) - sc-6902 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GDF-5/6/7/16 (A-2) - sc-374184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GDF-5/6/7/16 (A-2): sc-374184. Western blot analysis of mouse recombinant GDF-5.

Anti-GDF6 antibody - ab73288 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-GDF6 antibody (ab73288) at 0.5 µg/mlLane 2 : Anti-GDF6 antibody (ab73288) at 1 µg/mlLane 1 : SK-N-SH lysateLane 2 : SK-N-SH lysateLysates/proteins at 15 µg per lane.

Anti-GDF6 antibody - C-terminal - ab135661 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GDF6 antibody - C-terminal (ab135661) at 1/50 dilution + Mouse kidney tissue lysate at 35 µg

Anti-GDF6 antibody - N-terminal - ab170532 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GDF6 antibody - N-terminal (ab170532) at 1/50 dilution + Mouse liver tissue lysate at 35 µgdeveloped using the ECL technique

Anti-GDF6 / BMP13 Antibody (aa339-454, FITC) - LS-C302848 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GDF6 / BMP13 Antibody (aa339-454, Biotin) - LS-C300549 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GDF6 / BMP13 Antibody (C-Terminus) - LS-C83887 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of GDF6 in SK-N-SH lysate with GDF6 antibody at (A) 0.5 and (B) 1 ug/ml.

Anti-GDF6 / BMP13 Antibody (aa336-455) - LS-C294354 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant GDF6 / BMP13.

Anti-GDF6 / BMP13 Antibody (aa339-454) - LS-C294355 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant GDF6 / BMP13.

Anti-GDF6 / BMP13 Antibody - LS-C146966 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of GDF6 / BMP13 antibody LS-C146966.

Anti-GDF6 / BMP13 Antibody (aa31-59) - LS-C166429 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GDF6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-GDF6 / BMP13 Antibody (aa326-353) - LS-C100696 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

GDF-6/BMP-13 Antibody - NBP1-91934 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GDF6 Antibody [NBP1-91934] - Staining of human stomach, lower shows strong membranous and cytoplasmic positivity in glandular cells.

GDF-6/BMP-13 Antibody - NBP1-76364 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GDF-6/BMP-13 Antibody [NBP1-76364] - SK-N-SH lysate with GDF6 antibody at (A) 0.5 and (B) 1 ug/mL.

GDF-6/BMP-13 Antibody - NBP1-45406 from Novus Biologicals

Prices $245.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GDF-6/BMP-13 Antibody [NBP1-45406] - Analysis using recombinant human BMP-13. Both monome and dimer can be detected.

GDF6 Polyclonal Antibody - bs-11843R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11843R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11843R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11843R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11843R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, Cy3 Conjugated - bs-11843R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, Cy5 Conjugated - bs-11843R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, Cy5.5 Conjugated - bs-11843R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GDF6 Polyclonal Antibody, Cy7 Conjugated - bs-11843R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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