GDF6

Gene Symbol	GDF6
Entrez Gene	392255
Alt Symbol	BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1
Species	Human
Gene Type	protein-coding
Description	growth differentiation factor 6
Other Description	GDF-6|Klip-Feil malformation|Klippel-Feil malformation|Klippel-Feil syndrome|bone morphogenetic protein 13|growth/differentiation factor 16|growth/differentiation factor 6
Swissprots	Q6PI58 Q6KF10
Accessions	AGF34263 AGF34264 EAW91747 Q6KF10 AJ537424 CAD60934 BC043222 AAH43222 BC127947 AAI27948 BC127948 AAI27949 BC156445 AAI56446 XM_011517030 XP_011515332 NM_001001557 NP_001001557
Function	Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. May signal through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A. {ECO:0000269|PubMed:23307924}.
Subcellular Location	Secreted {ECO:0000269|PubMed:23307924}.
Top Pathways	TGF-beta signaling pathway, Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human GDF6 full length protein - ab50230 from Abcam Category Protein Source E. coli Species Human

GDF6 / BMP13 Antibody Blocking Peptide - LS-E1142 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GDF6 / BMP13 Antibody Blocking Peptide - LS-E8999 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GDF6 / BMP13 Antibody Blocking Peptide - LS-E30532 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human GDF-6/BMP-13 Protein - P4112 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Source E. coli Species Human

GDF-6/BMP-13 Blocking Peptide - NBP1-76364PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

GDF-6/BMP-13 Protein - NBP1-99133 from Novus Biologicals Category Protein Species Human

Recombinant Human GDF-6/BMP-13 Protein - NBP1-99870 from Novus Biologicals Category Protein Prices $190.00 Sizes 50 µg Source E. coli Species Human

GDF6-Antibody-N-term-Blocking-peptide - BP11672a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GDF6-Antibody-C-term-Blocking-Peptide - BP7483b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BMP-13 recombinant protein - GTX65478 from GeneTex Category Protein Prices $199.00 Sizes 10 μg Source E. coli Species Human

BMP-13 recombinant protein - GTX65477 from GeneTex Category Protein Prices $249.00 Sizes 50 μg Source E. coli Species Human

CDMP-2 Recombinant Protein (Active) - GTX48234-PRO from GeneTex Category Protein Prices $299.00 Sizes 50 μg Source E. coli Species Human

Human BMP-13 Protein (OPSA11768) - OPSA11768 from Aviva Systems Biology Category Protein Prices $440.00 Sizes 50 µg Species Human

BMP13 protein - 30R-2369 from Fitzgerald Category Protein Prices $125.00, $245.00 Sizes 10 µg, 50 µg Source E.coli Species Human

BMP13 protein - 30R-AB021 from Fitzgerald Category Protein Prices $95.00, $225.00 Sizes 10 µg, 50 µg Source E.coli

Human GDF6 Protein - abx066949 from Abbexa Category Protein Source E.coli Species Human

BMP13 / GDF6 - PA213 from Acris Antibodies Category Protein Prices $135.00 Sizes 10 µg Source E. coli Species Human

BMP13 / GDF6 - PA213X from Acris Antibodies Category Protein Prices $235.00 Sizes 50 µg Source E. coli Species Human

BMP13 / GDF6 - P4112 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

BMP13 / GDF6 Control Peptide - AP30360CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

BMP-13/CDMP-2, Recombinant Human - 213-10039-1 from RayBiotech Category Protein Prices $75.00 Sizes 1 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human BMP-13/CDMP-2 - 213-10039-2 from RayBiotech Category Protein Prices $190.00 Sizes 2 µg Source Escherichia coli (E.coli) Species Human

GDF6 Peptide - 4691P from ProSci Category Peptide Species Human

CDMP-2 Recombinant Protein - 40-202 from ProSci Category Protein Prices $150.00, $250.00 Sizes 10 µg, 50 µg Source E. coli Species Human

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