| Gene Symbol |
GNG11
|
| Entrez Gene |
2791
|
| Alt Symbol |
GNGT11
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), gamma 11
|
| Other Description |
G protein gamma-11 subunit|guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
|
| Swissprots |
P61952
|
| Accessions |
AAS02020 EAL24138 EAW76804 P61952 AF493878 AAM12592 AK312037 BAG34974 BC009709 AAH09709 BG255463 BT007141 AAP35805 DQ891427 ABM82353 DQ894602 ABM85528 U31384 AAC50206 NM_004126 NP_004117
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Tissue Specificity |
Abundantly expressed in all tissues tested except for brain.
|
| Top Pathways |
Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse
|