Gene Symbol | GNG11 |
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Entrez Gene | 2791 |
Alt Symbol | GNGT11 |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), gamma 11 |
Other Description | G protein gamma-11 subunit|guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-11 subunit|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 |
Swissprots | P61952 |
Accessions | AAS02020 EAL24138 EAW76804 P61952 AF493878 AAM12592 AK312037 BAG34974 BC009709 AAH09709 BG255463 BT007141 AAP35805 DQ891427 ABM82353 DQ894602 ABM85528 U31384 AAC50206 NM_004126 NP_004117 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Tissue Specificity | Abundantly expressed in all tissues tested except for brain. |
Top Pathways | Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse |
Gγ 11 CRISPR/Cas9 KO Plasmid (h) - sc-410797 from Santa Cruz Biotechnology
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Gγ 11 HDR Plasmid (h) - sc-410797-HDR from Santa Cruz Biotechnology
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Gγ 11 Double Nickase Plasmid (h) - sc-410797-NIC from Santa Cruz Biotechnology
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Gγ 11 Double Nickase Plasmid (h2) - sc-410797-NIC-2 from Santa Cruz Biotechnology
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Gγ 11 CRISPR Activation Plasmid (h) - sc-410797-ACT from Santa Cruz Biotechnology
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Gγ 11 CRISPR Activation Plasmid (h2) - sc-410797-ACT-2 from Santa Cruz Biotechnology
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Gγ 11 Lentiviral Activation Particles (h) - sc-410797-LAC from Santa Cruz Biotechnology
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Gγ 11 Lentiviral Activation Particles (h2) - sc-410797-LAC-2 from Santa Cruz Biotechnology
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G γ 11 siRNA (h) - sc-105378 from Santa Cruz Biotechnology
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G γ 11 shRNA Plasmid (h) - sc-105378-SH from Santa Cruz Biotechnology
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G γ 11 shRNA (h) Lentiviral Particles - sc-105378-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU033141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9424 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9424 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02607 from Sigma-Aldrich
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GNG11 siRNA (Human) - CRH1862 from Cohesion Biosciences
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GNG11 RNAi - H00002791-R01 from Novus Biologicals
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GNG11 - MBS8231645 from MyBioSource
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shRNA set against Human GNG11 (NM_004126.3) - SHH304854 from Creative biogene
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shRNA set against Human GNG11(NM_004126.3) - SHH092495 from Creative biogene
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GNG11 shRNA Plasmid (Human) - CHH1862 from Cohesion Biosciences
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GNG11 miRNA 3'UTR clone - MiUTR1H-04113 from Creative biogene
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