Gene Symbol |
HAO1
|
Entrez Gene |
54363
|
Alt Symbol |
GOX, GOX1, HAOX1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
hydroxyacid oxidase (glycolate oxidase) 1
|
Other Description |
(S)-2-hydroxy-acid oxidase|glycolate oxidase|hydroxyacid oxidase 1
|
Swissprots |
Q9Y3I7 Q9UPZ0 Q14CQ0 Q9UJM8
|
Accessions |
CBF69668 CBU94371 CCQ43554 EAX10379 EAX10380 EAX10381 Q9UJM8 AB024079 BAA82872 AF231916 AAF40199 AF244134 AAF63219 AK289423 BAF82112 AK308963 AK313839 BAG36571 AL121739 CAB57329 BC113665 AAI13666 BC113667 AAI13668 HQ258212 ADR82966 NM_017545 NP_060015
|
Function |
Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2- hydroxy octanoate. {ECO:0000269|PubMed:18215067}.
|
Subcellular Location |
Peroxisome.
|
Tissue Specificity |
Liver.
|
Top Pathways |
Peroxisome, Glyoxylate and dicarboxylate metabolism
|