Gene Symbol | HAO1 |
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Entrez Gene | 54363 |
Alt Symbol | GOX, GOX1, HAOX1 |
Species | Human |
Gene Type | protein-coding |
Description | hydroxyacid oxidase (glycolate oxidase) 1 |
Other Description | (S)-2-hydroxy-acid oxidase|glycolate oxidase|hydroxyacid oxidase 1 |
Swissprots | Q9Y3I7 Q9UPZ0 Q14CQ0 Q9UJM8 |
Accessions | CBF69668 CBU94371 CCQ43554 EAX10379 EAX10380 EAX10381 Q9UJM8 AB024079 BAA82872 AF231916 AAF40199 AF244134 AAF63219 AK289423 BAF82112 AK308963 AK313839 BAG36571 AL121739 CAB57329 BC113665 AAI13666 BC113667 AAI13668 HQ258212 ADR82966 NM_017545 NP_060015 |
Function | Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2- hydroxy octanoate. {ECO:0000269|PubMed:18215067}. |
Subcellular Location | Peroxisome. |
Tissue Specificity | Liver. |
Top Pathways | Peroxisome, Glyoxylate and dicarboxylate metabolism |
HAO1 CRISPR/Cas9 KO Plasmid (h) - sc-407493 from Santa Cruz Biotechnology
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HAO1 HDR Plasmid (h) - sc-407493-HDR from Santa Cruz Biotechnology
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HAO1 Double Nickase Plasmid (h) - sc-407493-NIC from Santa Cruz Biotechnology
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HAO1 Double Nickase Plasmid (h2) - sc-407493-NIC-2 from Santa Cruz Biotechnology
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HAO1 CRISPR Activation Plasmid (h) - sc-407493-ACT from Santa Cruz Biotechnology
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HAO1 CRISPR Activation Plasmid (h2) - sc-407493-ACT-2 from Santa Cruz Biotechnology
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HAO1 Lentiviral Activation Particles (h) - sc-407493-LAC from Santa Cruz Biotechnology
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HAO1 Lentiviral Activation Particles (h2) - sc-407493-LAC-2 from Santa Cruz Biotechnology
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HAO1 siRNA (h) - sc-75224 from Santa Cruz Biotechnology
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HAO1 shRNA Plasmid (h) - sc-75224-SH from Santa Cruz Biotechnology
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HAO1 shRNA (h) Lentiviral Particles - sc-75224-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU003781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9864 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9864 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05485 from Sigma-Aldrich
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HAO1 siRNA (Human) - CRJ0045 from Cohesion Biosciences
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HAO1 - MBS8238405 from MyBioSource
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shRNA set against Human HAO1 (NM_017545.2) - SHH310253 from Creative biogene
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shRNA set against Human HAO1(NM_017545.2) - SHH113717 from Creative biogene
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Human HAO1 siRNA - orb270546 from Biorbyt
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HAO1 shRNA Plasmid (Human) - CHJ0045 from Cohesion Biosciences
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HAO1 miRNA 3'UTR clone - MiUTR1H-04371 from Creative biogene
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