Gene Symbol | BHMT |
---|---|
Entrez Gene | 635 |
Alt Symbol | BHMT1, HEL-S-61p |
Species | Human |
Gene Type | protein-coding |
Description | betaine--homocysteine S-methyltransferase |
Other Description | betaine--homocysteine S-methyltransferase 1|epididymis secretory sperm binding protein Li 61p |
Swissprots | Q93088 Q9UNI9 |
Accessions | AAD22043 AAQ90058 EAW95831 EAW95832 Q93088 AK298308 BAG60562 AK303780 BAG64739 AK315224 BAG37653 BC012616 AAH12616 BM678994 DA370221 EU794592 ACJ13646 U50929 AAC50668 NM_001713 NP_001704 |
Function | Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Found exclusively in liver and kidney. {ECO:0000269|PubMed:9281325}. |
Top Pathways | Glycine, serine and threonine metabolism, Cysteine and methionine metabolism |
BHMT CRISPR/Cas9 KO Plasmid (h) - sc-405772 from Santa Cruz Biotechnology
|
||||||||
BHMT HDR Plasmid (h) - sc-405772-HDR from Santa Cruz Biotechnology
|
||||||||
BHMT Double Nickase Plasmid (h) - sc-405772-NIC from Santa Cruz Biotechnology
|
||||||||
BHMT Double Nickase Plasmid (h2) - sc-405772-NIC-2 from Santa Cruz Biotechnology
|
||||||||
BHMT CRISPR Activation Plasmid (h) - sc-405772-ACT from Santa Cruz Biotechnology
|
||||||||
BHMT CRISPR Activation Plasmid (h2) - sc-405772-ACT-2 from Santa Cruz Biotechnology
|
||||||||
BHMT Lentiviral Activation Particles (h) - sc-405772-LAC from Santa Cruz Biotechnology
|
||||||||
BHMT Lentiviral Activation Particles (h2) - sc-405772-LAC-2 from Santa Cruz Biotechnology
|
||||||||
BHMT siRNA (h) - sc-91965 from Santa Cruz Biotechnology
|
||||||||
BHMT shRNA Plasmid (h) - sc-91965-SH from Santa Cruz Biotechnology
|
||||||||
BHMT shRNA (h) Lentiviral Particles - sc-91965-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU052791 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3971 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3971 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR12567 from Sigma-Aldrich
|
||||||||
BHMT siRNA (Human) - CRH0431 from Cohesion Biosciences
|
||||||||
BHMT - MBS827941 from MyBioSource
|
||||||||
shRNA set against Human BHMT (NM_001713.2) - SHH246630 from Creative biogene
|
||||||||
shRNA set against Human BHMT(NM_001713.2) - SHG100375 from Creative biogene
|
||||||||
BHMT shRNA Plasmid (Human) - CHH0431 from Cohesion Biosciences
|
||||||||
BHMT miRNA 3'UTR clone - MiUTR1H-00884 from Creative biogene
|