Gene Symbol |
ETFB
|
Entrez Gene |
2109
|
Alt Symbol |
FP585, MADD
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
electron-transfer-flavoprotein, beta polypeptide
|
Other Description |
beta-ETF|electron transfer flavoprotein beta subunit|electron transfer flavoprotein beta-subunit|electron transfer flavoprotein subunit beta|electron transfer flavoprotein, beta polypeptide|electron-transferring-flavoprotein, beta polypeptide
|
Swissprots |
Q9Y3S7 B3KNY2 P38117 Q71RF6 Q6IBH7 A8K766
|
Accessions |
AAN03713 CAB37832 CBF67773 CBU92647 EAW72004 P38117 AF370381 AAQ15217 AK055285 BAG51494 AK128845 AK291881 BAF84570 AL833205 BC093961 AAH93961 BC093963 AAH93963 BG281641 BG399783 CR456827 CAG33108 X71129 CAA50441 NM_001014763 NP_001014763 NM_001985 NP_001976
|
Function |
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl- CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
|
Subcellular Location |
Mitochondrion matrix.
|
Tissue Specificity |
Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
|