Gene Symbol | ETFB |
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Entrez Gene | 2109 |
Alt Symbol | FP585, MADD |
Species | Human |
Gene Type | protein-coding |
Description | electron-transfer-flavoprotein, beta polypeptide |
Other Description | beta-ETF|electron transfer flavoprotein beta subunit|electron transfer flavoprotein beta-subunit|electron transfer flavoprotein subunit beta|electron transfer flavoprotein, beta polypeptide|electron-transferring-flavoprotein, beta polypeptide |
Swissprots | Q9Y3S7 B3KNY2 P38117 Q71RF6 Q6IBH7 A8K766 |
Accessions | AAN03713 CAB37832 CBF67773 CBU92647 EAW72004 P38117 AF370381 AAQ15217 AK055285 BAG51494 AK128845 AK291881 BAF84570 AL833205 BC093961 AAH93961 BC093963 AAH93963 BG281641 BG399783 CR456827 CAG33108 X71129 CAA50441 NM_001014763 NP_001014763 NM_001985 NP_001976 |
Function | The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl- CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas. |
ETFB CRISPR/Cas9 KO Plasmid (h) - sc-409609 from Santa Cruz Biotechnology
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ETFB HDR Plasmid (h) - sc-409609-HDR from Santa Cruz Biotechnology
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ETFB Double Nickase Plasmid (h) - sc-409609-NIC from Santa Cruz Biotechnology
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ETFB Double Nickase Plasmid (h2) - sc-409609-NIC-2 from Santa Cruz Biotechnology
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ETFB CRISPR Activation Plasmid (h) - sc-409609-ACT from Santa Cruz Biotechnology
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ETFB CRISPR Activation Plasmid (h2) - sc-409609-ACT-2 from Santa Cruz Biotechnology
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ETFB Lentiviral Activation Particles (h) - sc-409609-LAC from Santa Cruz Biotechnology
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ETFB Lentiviral Activation Particles (h2) - sc-409609-LAC-2 from Santa Cruz Biotechnology
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ETFB siRNA (h) - sc-97745 from Santa Cruz Biotechnology
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ETFB shRNA Plasmid (h) - sc-97745-SH from Santa Cruz Biotechnology
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ETFB shRNA (h) Lentiviral Particles - sc-97745-V from Santa Cruz Biotechnology
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ETFB RNAi - H00002109-R01 from Novus Biologicals
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ETFB RNAi - H00002109-R02 from Novus Biologicals
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MISSION® esiRNA - EHU041661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8002 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8002 from Sigma-Aldrich
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ETFB siRNA (Human) - CRH1464 from Cohesion Biosciences
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ETFB - MBS8228442 from MyBioSource
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shRNA set against Human ETFB (NM_001985.2) - SHH287577 from Creative biogene
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shRNA set against Human ETFB(NM_001985.2) - SHH040079 from Creative biogene
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shRNA set against Human ETFB(NM_001014763.1) - SHH040097 from Creative biogene
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Human ETFB siRNA - orb261966 from Biorbyt
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ETFB shRNA Plasmid (Human) - CHH1464 from Cohesion Biosciences
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ETFB miRNA 3'UTR clone - MiUTR1H-03318 from Creative biogene
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ETFB miRNA 3'UTR clone - MiUTR1H-03319 from Creative biogene
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