PNPLA8

Gene Symbol PNPLA8
Entrez Gene 50640
Alt Symbol IPLA2(GAMMA), IPLA2-2, IPLA2G, iPLA2gamma
Species Human
Gene Type protein-coding
Description patatin-like phospholipase domain containing 8
Other Description PNPLA-gamma|calcium-independent phospholipase A2-gamma|iPLA2 gamma|iPLA2-gamma|intracellular membrane-associated calcium-independent phospholipase A2 gamma|membrane-associated calcium-independent phospholipase A2 gamma|patatin-like phospholipase domain-containing protein 8
Swissprots Q8N3I3 Q9NUN2 O95035 Q9NR17 Q9H7T5 A4D0S1 C9JZI4 Q9NZ79 Q9NP80
Accessions AAD08847 EAL24384 EAL24385 EAW83432 EAW83433 EAW83434 EAW83435 Q9NP80 AB041261 BAA94997 AF217519 AAF67630 AF263613 AAF75269 AF263947 AAF81246 AK002115 BAA92090 AK024335 BAB14890 AK291755 BAF84444 AL834147 CAD38859 AM392663 CAL37541 BC005203 BC032999 AAH32999 BX647865 DQ890948 ABM81874 DQ894111 ABM85037 XM_005250396 XP_005250453 XM_011516274 XP_011514576 XM_011516275 XP_011514577 XR_927471 XR_927472 XR_927473 NM_001256007 NP_001242936 NM_001256008 NP_001242937 NM_001256009 NP_001242938 NM_001256010 NP_001242939 NM_001256011 NP_001242940 NM_015723 NP_056538
Function Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. {ECO:0000269|PubMed:10744668, ECO:0000269|PubMed:15695510}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}.
Tissue Specificity Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart. {ECO:0000269|PubMed:10744668, ECO:0000269|PubMed:10833412, ECO:0000269|PubMed:15629460, ECO:0000269|PubMed:15695510}.

iPLA 2 γ CRISPR/Cas9 KO Plasmid (h) - sc-409916 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ HDR Plasmid (h) - sc-409916-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ Double Nickase Plasmid (h) - sc-409916-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ Double Nickase Plasmid (h2) - sc-409916-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ CRISPR Activation Plasmid (h) - sc-409916-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ CRISPR Activation Plasmid (h2) - sc-409916-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ Lentiviral Activation Particles (h) - sc-409916-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ Lentiviral Activation Particles (h2) - sc-409916-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iPLA 2 γ siRNA (h) - sc-89772 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

iPLA 2 γ shRNA Plasmid (h) - sc-89772-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

iPLA 2 γ shRNA (h) Lentiviral Particles - sc-89772-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU065201 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17069 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17069 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06349 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06349

PNPLA8 siRNA (Human) - CRH9397 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PNPLA8 (NM_015723.3) - SHH378852 from Creative biogene

Category siRNA
Species Reactivities Human

Human PNPLA8 siRNA - orb269899 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PNPLA8 shRNA Plasmid (Human) - CHH9397 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PNPLA8 miRNA 3'UTR clone - MiUTR3H-12307 from Creative biogene

Species Reactivities Human
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