| Gene Symbol |
LEPROTL1
|
| Entrez Gene |
23484
|
| Alt Symbol |
HSPC112, Vps55, my047
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leptin receptor overlapping transcript-like 1
|
| Other Description |
endospanin-2
|
| Swissprots |
E9PHP8 O95214 Q9BW48
|
| Accessions |
CAH25986 CAH59518 CAI72073 CBX85063 EAW63468 EAW63469 EAW63470 O95214 AF063605 AAC98697 AF161461 AAF29076 AK075363 BAG52122 AY277595 AAQ18034 AY358674 AAQ89037 BC000642 AAH00642 CR541735 CAG46535 CR541760 CAG46560 DA258969 DQ891897 ABM82823 DQ895083 ABM86009 NM_001128208 NP_001121680 NM_015344 NP_056159
|
| Function |
Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. {ECO:0000269|PubMed:19907080}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed, with highest expression in heart, testis, adrenal gland, thymus, and spleen, and lowest expression in lung and skeletal muscle.
|