Gene Symbol | LEPROTL1 |
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Entrez Gene | 23484 |
Alt Symbol | HSPC112, Vps55, my047 |
Species | Human |
Gene Type | protein-coding |
Description | leptin receptor overlapping transcript-like 1 |
Other Description | endospanin-2 |
Swissprots | E9PHP8 O95214 Q9BW48 |
Accessions | CAH25986 CAH59518 CAI72073 CBX85063 EAW63468 EAW63469 EAW63470 O95214 AF063605 AAC98697 AF161461 AAF29076 AK075363 BAG52122 AY277595 AAQ18034 AY358674 AAQ89037 BC000642 AAH00642 CR541735 CAG46535 CR541760 CAG46560 DA258969 DQ891897 ABM82823 DQ895083 ABM86009 NM_001128208 NP_001121680 NM_015344 NP_056159 |
Function | Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. {ECO:0000269|PubMed:19907080}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed, with highest expression in heart, testis, adrenal gland, thymus, and spleen, and lowest expression in lung and skeletal muscle. |
LEPROTL1 CRISPR/Cas9 KO Plasmid (h) - sc-405575 from Santa Cruz Biotechnology
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LEPROTL1 HDR Plasmid (h) - sc-405575-HDR from Santa Cruz Biotechnology
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LEPROTL1 Double Nickase Plasmid (h) - sc-405575-NIC from Santa Cruz Biotechnology
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LEPROTL1 Double Nickase Plasmid (h2) - sc-405575-NIC-2 from Santa Cruz Biotechnology
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LEPROTL1 CRISPR Activation Plasmid (h) - sc-405575-ACT from Santa Cruz Biotechnology
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LEPROTL1 CRISPR Activation Plasmid (h2) - sc-405575-ACT-2 from Santa Cruz Biotechnology
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LEPROTL1 Lentiviral Activation Particles (h) - sc-405575-LAC from Santa Cruz Biotechnology
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LEPROTL1 Lentiviral Activation Particles (h2) - sc-405575-LAC-2 from Santa Cruz Biotechnology
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LEPROTL1 siRNA (h) - sc-77794 from Santa Cruz Biotechnology
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LEPROTL1 shRNA Plasmid (h) - sc-77794-SH from Santa Cruz Biotechnology
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LEPROTL1 shRNA (h) Lentiviral Particles - sc-77794-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU087161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11654 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11654 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11261 from Sigma-Aldrich
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LEPROTL1 siRNA (Human) - CRH8301 from Cohesion Biosciences
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shRNA set against Human LEPROTL1 (NM_015344.2) - SHH329687 from Creative biogene
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Human LEPROTL1 siRNA - orb268803 from Biorbyt
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LEPROTL1 shRNA Plasmid (Human) - CHH8301 from Cohesion Biosciences
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LEPROTL1 miRNA 3'UTR clone - MiUTR3H-09164 from Creative biogene
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