| Gene Symbol |
MITD1
|
| Entrez Gene |
129531
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MIT, microtubule interacting and transport, domain containing 1
|
| Other Description |
MIT domain-containing protein 1
|
| Swissprots |
Q8WV92 Q69YV0
|
| Accessions |
AAX88928 CAH25929 EAX01884 EAX01885 EAX01886 EAX01887 Q8WV92 AK311658 AL161992 CAH10777 BC018453 AAH18453 HQ447338 ADQ31824 XM_011510581 XP_011508883 XM_011510582 XP_011508884 XM_011510583 XP_011508885 XM_011510584 XP_011508886 NM_138798 NP_620153
|
| Function |
Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. {ECO:0000269|PubMed:23015756, ECO:0000269|PubMed:23045692}.
|
| Subcellular Location |
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Midbody. Membrane; Peripheral membrane protein; Cytoplasmic side. Note=During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in phosphoinositides.
|
![Western Blot: MITD1 Overexpression Lysate (Adult Normal) [NBL1-13116] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MITD1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8661_MITD1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-13116-img0002.jpg)