Gene Symbol | MITD1 |
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Entrez Gene | 129531 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | MIT, microtubule interacting and transport, domain containing 1 |
Other Description | MIT domain-containing protein 1 |
Swissprots | Q8WV92 Q69YV0 |
Accessions | AAX88928 CAH25929 EAX01884 EAX01885 EAX01886 EAX01887 Q8WV92 AK311658 AL161992 CAH10777 BC018453 AAH18453 HQ447338 ADQ31824 XM_011510581 XP_011508883 XM_011510582 XP_011508884 XM_011510583 XP_011508885 XM_011510584 XP_011508886 NM_138798 NP_620153 |
Function | Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. {ECO:0000269|PubMed:23015756, ECO:0000269|PubMed:23045692}. |
Subcellular Location | Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Midbody. Membrane; Peripheral membrane protein; Cytoplasmic side. Note=During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in phosphoinositides. |
MITD1 CRISPR/Cas9 KO Plasmid (h) - sc-414352 from Santa Cruz Biotechnology
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MITD1 HDR Plasmid (h) - sc-414352-HDR from Santa Cruz Biotechnology
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MITD1 Double Nickase Plasmid (h) - sc-414352-NIC from Santa Cruz Biotechnology
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MITD1 Double Nickase Plasmid (h2) - sc-414352-NIC-2 from Santa Cruz Biotechnology
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MITD1 CRISPR Activation Plasmid (h) - sc-414352-ACT from Santa Cruz Biotechnology
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MITD1 CRISPR Activation Plasmid (h2) - sc-414352-ACT-2 from Santa Cruz Biotechnology
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MITD1 Lentiviral Activation Particles (h) - sc-414352-LAC from Santa Cruz Biotechnology
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MITD1 Lentiviral Activation Particles (h2) - sc-414352-LAC-2 from Santa Cruz Biotechnology
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MITD1 siRNA (h) - sc-94910 from Santa Cruz Biotechnology
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MITD1 shRNA Plasmid (h) - sc-94910-SH from Santa Cruz Biotechnology
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MITD1 shRNA (h) Lentiviral Particles - sc-94910-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU153621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14372 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14372 from Sigma-Aldrich
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MITD1 siRNA (Human) - CRJ5003 from Cohesion Biosciences
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shRNA set against Human MITD1 (NM_138798.1) - SHH342196 from Creative biogene
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shRNA set against Human MITD1(NM_138798.1) - SHH190685 from Creative biogene
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MITD1 shRNA Plasmid (Human) - CHJ5003 from Cohesion Biosciences
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MITD1 miRNA 3'UTR clone - MiUTR1H-06310 from Creative biogene
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