Rapgef4

Gene Symbol Rapgef4
Entrez Gene 56508
Alt Symbol 1300003D15Rik, 5730402K07Rik, 6330581N18Rik, EPAC 2, Epac-2, Epac2, mKIAA4040
Species Mouse
Gene Type protein-coding
Description Rap guanine nucleotide exchange factor (GEF) 4
Other Description cAMP-GEFII|cAMP-dependent Rap1 guanine-nucleotide exchange factor|cAMP-regulated guanine nucleotide exchange factor IIB|exchange factor directly activated by cAMP 2|exchange protein directly activated by cAMP 2|rap guanine nucleotide exchange factor 4
Swissprots Q9Z1P0 Q9CW52 Q8VIP9 Q9EQZ6
Accessions CDM22141 EDL27106 EDL27107 EDL27108 Q9EQZ6 AB021132 BAB18976 AB037668 BAB72180 AB445011 BAH30656 AF115480 AAD09132 AK004874 BAB23633 AK017479 BAB30763 AK032089 AK046900 AK080066 AK135084 AK161934 AK203721 AK220281 BAD90206 BC139822 AAI39823 BP767789 CK622268 XM_006499938 XP_006500001 XM_011239711 XP_011238013 NM_001204165 NP_001191094 NM_001204166 NP_001191095 NM_001204167 NP_001191096 NM_019688 NP_062662
Function Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA- independent exocytosis through interaction with RIMS2. {ECO:0000269|PubMed:11056535}.
Subcellular Location Cytoplasm. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Expressed in cerebellum, pituitary, adrenal gland and liver. {ECO:0000269|PubMed:11056535}.
Top Pathways Leukocyte transendothelial migration, Adrenergic signaling in cardiomyocytes, cAMP signaling pathway, Rap1 signaling pathway

Epac2 CRISPR/Cas9 KO Plasmid (m) - sc-425208 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 HDR Plasmid (m) - sc-425208-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 Double Nickase Plasmid (m) - sc-425208-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 Double Nickase Plasmid (m2) - sc-425208-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 CRISPR Activation Plasmid (m) - sc-425208-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 CRISPR Activation Plasmid (m2) - sc-425208-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 Lentiviral Activation Particles (m) - sc-425208-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 Lentiviral Activation Particles (m2) - sc-425208-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Epac2 siRNA (m) - sc-41703 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Epac2 shRNA Plasmid (m) - sc-41703-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Epac2 shRNA (m) Lentiviral Particles - sc-41703-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU047541 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN39892 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39892 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RAPGEF4 siRNA (Mouse) - CRM5841 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

RAPGEF4 - MBS8220778 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse RAPGEF4 (NM_019688.2) - SHH389692 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse RAPGEF4 siRNA - orb285317 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

RAPGEF4 shRNA Plasmid (Mouse) - CHM5841 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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