Gene Symbol | EFTUD1 |
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Entrez Gene | 79631 |
Alt Symbol | FAM42A, HsT19294, RIA1 |
Species | Human |
Gene Type | protein-coding |
Description | elongation factor Tu GTP binding domain containing 1 |
Other Description | elongation factor Tu GTP-binding domain-containing protein 1|elongation factor-like 1|ribosome assembly 1 homolog |
Swissprots | B7Z6I0 Q9H8Z6 A6NKY5 Q7Z2Z2 |
Accessions | EAW99087 EAW99088 EAW99089 Q7Z2Z2 AK023181 BAB14450 AK056656 BAG51777 AK300348 BAH13266 BC014628 BC041565 BC152910 AAI52911 BC156743 AAI56744 BG204990 BX538332 CAD98101 DA260259 XM_011521998 XP_011520300 XM_011521999 XP_011520301 XM_011522000 XP_011520302 XR_931901 NM_001040610 NP_001035700 NM_024580 NP_078856 |
Function | Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits. {ECO:0000269|PubMed:21536732}. |
Top Pathways | Ribosome biogenesis in eukaryotes |
RIA1 (C-5) - sc-398435 from Santa Cruz Biotechnology
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RIA1 (C-15) - sc-240829 from Santa Cruz Biotechnology
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RIA1 (S-18) - sc-240828 from Santa Cruz Biotechnology
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Anti-EFTUD1 antibody - ab188305 from Abcam
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Anti-EFTUD1 Antibody (aa1062-1090) - LS-C167653 from LifeSpan Bioscience
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Anti-EFTUD1 Antibody (aa1062-1090, Biotin) - LS-C256517 from LifeSpan Bioscience
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Anti-EFTUD1 Antibody (aa1062-1090, AP) - LS-C256516 from LifeSpan Bioscience
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Anti-EFTUD1 Antibody (aa1062-1090, Azide-free, HRP) - LS-C256519 from LifeSpan Bioscience
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Anti-EFTUD1 Antibody (aa1062-1090, FITC) - LS-C256518 from LifeSpan Bioscience
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Anti-EFTUD1 Antibody (aa1062-1090, PE) - LS-C256520 from LifeSpan Bioscience
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Anti-EFTUD1 Antibody (aa1062-1090, APC) - LS-C256515 from LifeSpan Bioscience
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Anti-EFTUD1 Antibody (aa1069-1098) - LS-C321035 from LifeSpan Bioscience
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EFTUD1 Antibody - NBP2-32619 from Novus Biologicals
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EFTUD1 Antibody - NBP2-33646 from Novus Biologicals
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EFTUD1 Antibody - NBP2-33478 from Novus Biologicals
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ANTI-EFTUD1 (C-TERM) antibody produced in rabbit - SAB1301151 from Sigma-Aldrich
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Anti-EFTUD1 antibody produced in rabbit - HPA039654 from Sigma-Aldrich
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Anti-EFTUD1 antibody produced in rabbit - HPA052345 from Sigma-Aldrich
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Anti-EFTUD1 antibody produced in rabbit - HPA047110 from Sigma-Aldrich
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EFTUD1 Antibody - C-terminal region (ARP68287_P050) - ARP68287_P050 from Aviva Systems Biology
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EFTUD1 Antibody - N-terminal region (ARP68288_P050) - ARP68288_P050 from Aviva Systems Biology
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EFTUD1 Antibody - C-terminal region (OAAB00382) - OAAB00382 from Aviva Systems Biology
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EFTUD1-Antibody-C-term - AP10373b from Abgent, a WuXi AppTec company
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Anti -EFTUD1, CT (EFTUD1, EFL1, FAM42A, Elongation factor Tu GTP-binding domain-containingprotein 1, Elongation factor-like 1, Protein FAM42A) - 034955 from USBiological Life Science
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Anti -EFTUD1, CT (EFTUD1, EFL1, FAM42A, Elongation factor Tu GTP-binding domain-containingprotein 1, Elongation factor-like 1, Protein FAM42A) (AP) - 034955-AP from USBiological Life Science
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