| Gene Symbol | PRDX6 |
|---|---|
| Entrez Gene | 9588 |
| Alt Symbol | 1-Cys, AOP2, HEL-S-128m, NSGPx, PRX, aiPLA2, p29 |
| Species | Human |
| Gene Type | protein-coding |
| Description | peroxiredoxin 6 |
| Other Description | 1-Cys PRX|1-Cys peroxiredoxin|24 kDa protein|acidic calcium-independent phospholipase A2|antioxidant protein 2|epididymis secretory sperm binding protein Li 128m|liver 2D page spot 40|non-selenium glutathione peroxidase|peroxiredoxin-6|red blood cells page spot 12 |
| Swissprots | A8JZY7 Q5ZEZ8 P30041 P32077 Q5TAH4 |
| Accessions | ABB02185 CBX32674 EAW90944 EAW90945 P30041 AJ844621 CAH59743 AJ844622 AK095940 AK289352 BAF82041 AK300680 BAG62363 BC025421 BC035857 AAH35857 BC053550 AAH53550 D14662 BAA03496 EF036493 ABO65079 EU794652 ACJ13706 HQ448177 ADQ32658 NM_004905 NP_004896 |
| Function | Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16186110, ECO:0000269|PubMed:19188445}. Lysosome {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Also found in lung secretory organelles. {ECO:0000250}. |
| Top Pathways | Phenylalanine metabolism |