Gene Symbol | PRDX6 |
---|---|
Entrez Gene | 9588 |
Alt Symbol | 1-Cys, AOP2, HEL-S-128m, NSGPx, PRX, aiPLA2, p29 |
Species | Human |
Gene Type | protein-coding |
Description | peroxiredoxin 6 |
Other Description | 1-Cys PRX|1-Cys peroxiredoxin|24 kDa protein|acidic calcium-independent phospholipase A2|antioxidant protein 2|epididymis secretory sperm binding protein Li 128m|liver 2D page spot 40|non-selenium glutathione peroxidase|peroxiredoxin-6|red blood cells page spot 12 |
Swissprots | A8JZY7 Q5ZEZ8 P30041 P32077 Q5TAH4 |
Accessions | ABB02185 CBX32674 EAW90944 EAW90945 P30041 AJ844621 CAH59743 AJ844622 AK095940 AK289352 BAF82041 AK300680 BAG62363 BC025421 BC035857 AAH35857 BC053550 AAH53550 D14662 BAA03496 EF036493 ABO65079 EU794652 ACJ13706 HQ448177 ADQ32658 NM_004905 NP_004896 |
Function | Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16186110, ECO:0000269|PubMed:19188445}. Lysosome {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Also found in lung secretory organelles. {ECO:0000250}. |
Top Pathways | Phenylalanine metabolism |
PRX VI CRISPR/Cas9 KO Plasmid (h) - sc-401549 from Santa Cruz Biotechnology
|
||||||||
PRX VI HDR Plasmid (h) - sc-401549-HDR from Santa Cruz Biotechnology
|
||||||||
PRX VI Double Nickase Plasmid (h) - sc-401549-NIC from Santa Cruz Biotechnology
|
||||||||
PRX VI Double Nickase Plasmid (h2) - sc-401549-NIC-2 from Santa Cruz Biotechnology
|
||||||||
PRX VI CRISPR Activation Plasmid (h) - sc-401549-ACT from Santa Cruz Biotechnology
|
||||||||
PRX VI CRISPR Activation Plasmid (h2) - sc-401549-ACT-2 from Santa Cruz Biotechnology
|
||||||||
PRX VI Lentiviral Activation Particles (h) - sc-401549-LAC from Santa Cruz Biotechnology
|
||||||||
PRX VI Lentiviral Activation Particles (h2) - sc-401549-LAC-2 from Santa Cruz Biotechnology
|
||||||||
PRX VI siRNA (h) - sc-62896 from Santa Cruz Biotechnology
|
||||||||
PRX VI shRNA Plasmid (h) - sc-62896-SH from Santa Cruz Biotechnology
|
||||||||
PRX VI shRNA (h) Lentiviral Particles - sc-62896-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU013621 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN17387 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17387 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR08312 from Sigma-Aldrich
|
||||||||
PRDX6 siRNA (Human) - CRH6382 from Cohesion Biosciences
|
||||||||
shRNA set against Human PRD (NM_004905.2) - SHH382124 from Creative biogene
|
||||||||
shRNA set against Human PRDX6(NM_004905.2) - SHR138316 from Creative biogene
|
||||||||
PRDX6 shRNA Plasmid (Human) - CHH6382 from Cohesion Biosciences
|
||||||||
PRDX6 miRNA 3'UTR clone - MiUTR1H-08238 from Creative biogene
|