| Gene Symbol |
PRDX6
|
| Entrez Gene |
9588
|
| Alt Symbol |
1-Cys, AOP2, HEL-S-128m, NSGPx, PRX, aiPLA2, p29
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
peroxiredoxin 6
|
| Other Description |
1-Cys PRX|1-Cys peroxiredoxin|24 kDa protein|acidic calcium-independent phospholipase A2|antioxidant protein 2|epididymis secretory sperm binding protein Li 128m|liver 2D page spot 40|non-selenium glutathione peroxidase|peroxiredoxin-6|red blood cells page spot 12
|
| Swissprots |
A8JZY7 Q5ZEZ8 P30041 P32077 Q5TAH4
|
| Accessions |
ABB02185 CBX32674 EAW90944 EAW90945 P30041 AJ844621 CAH59743 AJ844622 AK095940 AK289352 BAF82041 AK300680 BAG62363 BC025421 BC035857 AAH35857 BC053550 AAH53550 D14662 BAA03496 EF036493 ABO65079 EU794652 ACJ13706 HQ448177 ADQ32658 NM_004905 NP_004896
|
| Function |
Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16186110, ECO:0000269|PubMed:19188445}. Lysosome {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Also found in lung secretory organelles. {ECO:0000250}.
|
| Top Pathways |
Phenylalanine metabolism
|
![Western Blot: Peroxiredoxin-6 Overexpression Lysate (Adult Normal) [NBL1-14743] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Peroxiredoxin-6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1187_Peroxiredoxin-6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14743-img0002.jpg)