Gene Symbol | CDKN2C |
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Entrez Gene | 1031 |
Alt Symbol | INK4C, p18, p18-INK4C |
Species | Human |
Gene Type | protein-coding |
Description | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
Other Description | CDK6 inhibitor p18|cyclin-dependent inhibitor|cyclin-dependent kinase 4 inhibitor C|cyclin-dependent kinase 6 inhibitor p18|p18-INK6 |
Swissprots | Q8TB83 P42773 |
Accessions | AAC39783 AAF28398 AAM11873 CBX47327 EAX06833 EAX06834 EAX06835 EAX06836 P42773 AF041248 AAC39782 AK021794 AK091170 BAG52297 BC000598 AAH00598 BC005041 AAH05041 BC016173 AAH16173 BC017036 BE783451 BE831176 CR450289 CAG29285 DQ891516 ABM82442 DQ894707 ABM85633 U17074 AAC50074 NM_001262 NP_001253 NM_078626 NP_523240 |
Function | Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. |
Tissue Specificity | Highest levels found in skeletal muscle. Also found in pancreas and heart. |
Top Pathways | Cell cycle, HTLV-I infection, Transcriptional misregulation in cancer |
Human p18 INK4c full length protein - ab119460 from Abcam
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Human p18 INK4c full length protein - ab85605 from Abcam
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Human p18 INK4c full length protein - ab40127 from Abcam
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Human p18 INK4c peptide - ab71845 from Abcam
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CDKN2C / p18 INK4c Antibody Blocking Peptide - LS-E620 from LifeSpan Bioscience
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p18INK4c/CDKN2C Recombinant Protein - H00001031-P01 from Novus Biologicals
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Recombinant Human p18INK4c/CDKN2C Protein - NBP1-78876 from Novus Biologicals
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CDKN2C-Antibody-C-term-Blocking-peptide - BP10954b from Abgent, a WuXi AppTec company
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p18 INK4c Protein - GTX108593-pro from GeneTex
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CDKN2C Protein Lysate (APL10264) - APL10264 from Aviva Systems Biology
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Human CDKN2C protein - orb168095 from Biorbyt
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Human CDKN2C protein - orb49328 from Biorbyt
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CDKN2C protein (His tag) - 80R-2119 from Fitzgerald
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CDKN2C / p18INK4c - H00001031-P01-10 from Acris Antibodies
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CDKN2C / p18INK4c - H00001031-P01-25 from Acris Antibodies
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CDKN2C, 1-168aa, Human, His tag, E.coli - 01-P1377 from ARP American Research Products
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Cyclin-Dependent Kinase 4 Inhibitor C, CDKN2C, Human, Recombinant - 19-C243 from ARP American Research Products
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CDKN2C fusion protein - ag3655 from Proteintech Group
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CDKN2C fusion protein - Ag15409 from Proteintech Group
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CDKN2C Human - PKPS-027 from NeoScientific
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Recombinant Human CDKN2C Enzyme - BP001129-C243 from Syd Labs
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Recombinant Human CDKN2C Enzyme - BP001129-PKA-020 from Syd Labs
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CDKN2C, 1-168aa, Recombinant Protein - GWB-P0661K from Genway Biotech
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Recombinant Human CDKN2C, GST-tagged - CDKN2C-1475H from Creative Biomart
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Recombinant Human CDKN2C, T7-tagged - CDKN2C-3049H from Creative Biomart
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