TNFRSF25

Gene Symbol	TNFRSF25
Entrez Gene	8718
Alt Symbol	APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 25
Other Description	apoptosis inducing receptor|apoptosis-inducing receptor AIR|apoptosis-mediating receptor DR3|apoptosis-mediating receptor TRAMP|death domain receptor 3 soluble form|death receptor beta|lymphocyte-associated receptor of death|protein WSL-1|tumor necrosis factor receptor superfamily member 25|tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
Swissprots	Q9UME5 B7ZLL7 Q17RU4 Q93036 Q9UME1 O00279 Q93038 Q99831 O14865 Q9UME0 Q93037 Q99722 O00276 Q92983 B1ALX3 P78515 O00277 O00280 B1ALX2 P78507 O00275 O00278 Q9BY86 Q99830 O14866
Accessions	AAB41434 AAB41435 AAO63495 BAB40662 BAB40663 CAI48017 EAW71540 EAW71541 EAW71542 EAW71543 EAW71544 EAW71545 EAW71546 EAW71547 EAW71548 EAW71549 Q93038 AB308321 BAF64192 AF026070 AAC39556 AF026071 AAB82288 AK094463 BAG52869 AY358309 AAQ88676 BC117189 AAI17190 BC143886 AAI43887 BM666370 HQ258574 ADR83328 U72763 AAC50819 U74611 AAB39714 U75380 AAC51192 U75381 AAC51193 U78029 AAB40918 U83597 AAB41432 U83598 AAB41433 U94501 AAC51306 U94502 AAC51307 U94503 AAC51308 U94504 AAC51309 U94505 AAC51310 U94506 AAC51311 U94507 AAC51312 U94508 AAC51313 U94509 AAC51314 U94510 AAC51315 U94512 AAC51316 Y09392 CAA70559 NM_001039664 NP_001034753 NM_003790 NP_003781 NM_148965 NP_683866 NM_148966 NP_683867 NM_148967 NP_683868 NM_148970 NP_683871 NM_148968 NM_148969 NM_148974
Function	Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Subcellular Location	Isoform 10: Secreted.
Tissue Specificity	Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
Top Pathways	Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DR3 peptide - ab200666 from Abcam Category Peptide Prices $250.00 Sizes 50 µg

Human DR3 peptide - ab8443 from Abcam Category Peptide Species Human

Human DR3 peptide - ab8444 from Abcam Category Peptide Species Human

Human DR3 peptide - ab8445 from Abcam Category Peptide Species Human

Human DR3 protein fragment - ab160160 from Abcam Category Protein Source Wheat germ Species Human

Human DR3 protein fragment - ab157260 from Abcam Category Protein Source HEK 293 cells Species Human

TNFRSF25 / DR3 Antibody Blocking Peptide - LS-E4968 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNFRSF25 / DR3 Antibody Blocking Peptide - LS-E10656 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNFRSF25 / DR3 Antibody Blocking Peptide - LS-E35588 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TNFRSF25 / DR3 Antibody Blocking Peptide - LS-E29857 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TNFRSF25 / DR3 Antibody Blocking Peptide - LS-E29861 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TNFRSF25 / DR3 Antibody Blocking Peptide - LS-E29841 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

DR3/TNFRSF25 Partial Recombinant Protein - H00008718-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DR3/TNFRSF25 Peptide - NBP1-77019PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

DR3/TNFRSF25 Blocking Peptide - NBP1-76478PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

DR3/TNFRSF25 Blocking Peptide - NBP1-76474PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

DR3/TNFRSF25 Recombinant Protein - P4936 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 25 µg Species Human

TNFRSF25-Antibody-Center-Blocking-Peptide - BP17360c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNFRSF25-Antibody-C-term-Blocking-Peptide - BP8997b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DR3 peptide - GTX28443 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

DR3 peptide - GTX28444 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

DR3 peptide - GTX28445 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

Recombinant Human DR3/TNFRSF25 Fc Chimera, CF - 943-D3-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human TNFRSF25 Fc tag protein - orb84017 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Apo3 Blocking Peptide - 33R-10610 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

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