TNFRSF25

Gene Symbol TNFRSF25
Entrez Gene 8718
Alt Symbol APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 25
Other Description apoptosis inducing receptor|apoptosis-inducing receptor AIR|apoptosis-mediating receptor DR3|apoptosis-mediating receptor TRAMP|death domain receptor 3 soluble form|death receptor beta|lymphocyte-associated receptor of death|protein WSL-1|tumor necrosis factor receptor superfamily member 25|tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
Swissprots Q9UME5 B7ZLL7 Q17RU4 Q93036 Q9UME1 O00279 Q93038 Q99831 O14865 Q9UME0 Q93037 Q99722 O00276 Q92983 B1ALX3 P78515 O00277 O00280 B1ALX2 P78507 O00275 O00278 Q9BY86 Q99830 O14866
Accessions AAB41434 AAB41435 AAO63495 BAB40662 BAB40663 CAI48017 EAW71540 EAW71541 EAW71542 EAW71543 EAW71544 EAW71545 EAW71546 EAW71547 EAW71548 EAW71549 Q93038 AB308321 BAF64192 AF026070 AAC39556 AF026071 AAB82288 AK094463 BAG52869 AY358309 AAQ88676 BC117189 AAI17190 BC143886 AAI43887 BM666370 HQ258574 ADR83328 U72763 AAC50819 U74611 AAB39714 U75380 AAC51192 U75381 AAC51193 U78029 AAB40918 U83597 AAB41432 U83598 AAB41433 U94501 AAC51306 U94502 AAC51307 U94503 AAC51308 U94504 AAC51309 U94505 AAC51310 U94506 AAC51311 U94507 AAC51312 U94508 AAC51313 U94509 AAC51314 U94510 AAC51315 U94512 AAC51316 Y09392 CAA70559 NM_001039664 NP_001034753 NM_003790 NP_003781 NM_148965 NP_683866 NM_148966 NP_683867 NM_148967 NP_683868 NM_148970 NP_683871 NM_148968 NM_148969 NM_148974
Function Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Subcellular Location Isoform 10: Secreted.
Tissue Specificity Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
Top Pathways Cytokine-cytokine receptor interaction

DR3 CRISPR/Cas9 KO Plasmid (h) - sc-403461 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 HDR Plasmid (h) - sc-403461-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 Double Nickase Plasmid (h) - sc-403461-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 Double Nickase Plasmid (h2) - sc-403461-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 CRISPR Activation Plasmid (h) - sc-403461-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 CRISPR Activation Plasmid (h2) - sc-403461-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 Lentiviral Activation Particles (h) - sc-403461-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 Lentiviral Activation Particles (h2) - sc-403461-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR3 siRNA (h) - sc-35216 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DR3 shRNA Plasmid (h) - sc-35216-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DR3 shRNA (h) Lentiviral Particles - sc-35216-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DR3/TNFRSF25 RNAi - H00008718-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DR3/TNFRSF25 RNAi - H00008718-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DR3/TNFRSF25 RNAi - H00008718-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DR3/TNFRSF25 RNAi - H00008718-R05 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

DR3/TNFRSF25 RNAi - H00008718-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21754 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21754 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TNFRSF25 siRNA (Human) - CRH5739 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DR3/TNFRSF25 RNAi - H00008718-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TNFRSF25 - MBS8210377 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFRSF25 (NM_003790.2) - SHH432028 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF25(NM_003790.2) - SHL085062 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF25(NM_148970.1) - SHL085080 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF25(NM_148966.1) - SHL085098 from Creative biogene

Category siRNA
Species Reactivities Human
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