GRIA3

Gene Symbol GRIA3
Entrez Gene 2892
Alt Symbol GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94
Species Human
Gene Type protein-coding
Description glutamate receptor, ionotropic, AMPA 3
Other Description AMPA-selective glutamate receptor 3|dJ1171F9.1|gluR-3|glutamate receptor 3|glutamate receptor C|glutamate receptor subunit 3|glutamate receptor, ionotrophic, AMPA 3
Swissprots Q9HDA1 Q4VXD5 D3DTF1 Q9P0H1 Q9HDA2 Q4VXD6 P42263 Q9HDA0
Accessions AAF23961 AAF61847 AAF61848 AAF97857 AAF97858 AAF97859 EAX11865 EAX11866 EAX11867 P42263 AK297136 BAH12506 AW166130 BC032004 AAH32004 BC117464 AAI17465 BE504553 BY799542 DA158269 DA179917 DA180344 DA191279 DB505790 HQ258659 ADR83410 U10301 AAA67922 U10302 AAA67923 NM_000828 NP_000819 NM_001256743 NP_001243672 NM_007325 NP_015564 NM_181894
Function Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. {ECO:0000269|PubMed:21172611}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=Interaction with CNIH2 and CNIH3 promotes cell surface expression. {ECO:0000250}.
Top Pathways cAMP signaling pathway, Circadian entrainment, Retrograde endocannabinoid signaling, Nicotine addiction, Amphetamine addiction

AMPA Receptor (GluR 3) Antibody - 3437 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from rat brain and human cerebellum using AMPA Receptor (GluR 3) Antibody.

AMPA Receptor (GluR 3) (D25G9) Rabbit mAb - 5117 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D25G9
Western blot analysis of extracts from mouse and rat brains using AMPA Receptor (GluR 3) (D25G9) Rabbit mAb.

AMPA Receptor (GluR 3) (D47E3) Rabbit mAb - 4676 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (20 western blots)
Host Rabbit
Clonality Monoclonal
Clone D47E3
Western blot analysis of extracts from mouse and rat brains using AMPA Receptor (GluR 3) (D47E3) Rabbit mAb.

GluR-3 (H-14) - sc-34066 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GluR-3 (H-14): sc-34066. Western blot analysis of GluR-3 expression in T98G whole cell lysate.

GluR-3 (N-19) - sc-7613 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GluR-3 (N-19): sc-7613. Western blot analysis of glutamate receptor-3 (GluR-3) expression in rat (A) and mouse (B) brain tissue extracts.

GluR-3 (C-20) - sc-7612 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GluR-3 (C-20): sc-7612. Western blot analysis of GluR-3 expression in rat brain (A) and mouse brain (B) tissue extracts.

Anti-Glutamate receptor 3 antibody - ab187754 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Glutamate receptor 3 antibody [1D2] - ab130259 from Abcam

Host Mouse
Clonality Monoclonal
Clone 1D2
All lanes : Anti-Glutamate receptor 3 antibody [1D2] (ab130259) at 1/500 dilutionLane 1 : HEK293 cell lysate, untransfectedLane 2 : HEK293 cell lysate, transfected with Human Glutamate receptor 3-hIgGFc

Anti-Glutamate receptor 3 antibody [EP813Y] - ab40845 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP813Y
Anti-Glutamate receptor 3 antibody [EP813Y] (ab40845) at 1/5000 dilution + human brain lysate at 10 µg

Anti-Glutamate receptor 3 antibody - C-terminal - ab87609 from Abcam

Host Rabbit
Clonality Polyclonal
ICC/IF image of ab87609 stained PC12 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab87609, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h.Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-GRIA3 / GLUR3 Antibody (aa188-217, AP) - LS-C214941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody (aa188-217, APC) - LS-C214942 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody (aa201-250) - LS-C135030 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GRIA3 / GLUR3 antibody LS-C135030 Western blot of Mouse Liver lysate.

Anti-GRIA3 / GLUR3 Antibody (aa651-700) - LS-C169522 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody (aa188-217, FITC) - LS-C214944 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody (aa188-217, Biotin) - LS-C214943 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody (aa188-217) - LS-C166668 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GRIA3 Antibody western blot of WiDr cell line lysates (35 ug/lane). The GRIA3 antibody detected the GRIA3 protein (arrow).

Anti-GRIA3 / GLUR3 Antibody (aa188-217, Azide-free, HRP) - LS-C214945 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody (clone 3D10) - LS-C197350 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D10
Detection limit for recombinant GST tagged GRIA3 is 3 ng/ml as a capture antibody.

Anti-GRIA3 / GLUR3 Antibody (aa188-217, PE) - LS-C214946 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody - LS-C192413 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of GRIA3 pAb in extracts from mouse brain tissue.

Anti-GRIA3 / GLUR3 Antibody (aa187-217) - LS-C321784 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIA3 / GLUR3 Antibody (aa394-412) - LS-C313523 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of GRIA3 / GLUR3 antibody. All lanes: Anti-GRIA3 at 0.5ug/ml. Lane 1: Rat Brain Tissue Lysate at 40ug. Lane 2: Mouse Brain Tissue Lysate at 40ug. Predicted bind size: 101KD. Observed bind size: 101KD.

Anti-GRIA3 / GLUR3 Antibody (clone EP813Y) IHC-plus™ - LS-B8956 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EP813Y
Anti-GRIA3 / GLUR3 antibody IHC staining of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GRIA3 / GLUR3 Antibody (clone 1D2) - LS-C169383 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D2
IHC of paraffin-embedded human brain tissues (left) and rat brain tissues (right) using GRIA3 mouse monoclonal antibody with DAB staining.
Search more