GRIA3

Gene Symbol	GRIA3
Entrez Gene	2892
Alt Symbol	GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, AMPA 3
Other Description	AMPA-selective glutamate receptor 3|dJ1171F9.1|gluR-3|glutamate receptor 3|glutamate receptor C|glutamate receptor subunit 3|glutamate receptor, ionotrophic, AMPA 3
Swissprots	Q9HDA1 Q4VXD5 D3DTF1 Q9P0H1 Q9HDA2 Q4VXD6 P42263 Q9HDA0
Accessions	AAF23961 AAF61847 AAF61848 AAF97857 AAF97858 AAF97859 EAX11865 EAX11866 EAX11867 P42263 AK297136 BAH12506 AW166130 BC032004 AAH32004 BC117464 AAI17465 BE504553 BY799542 DA158269 DA179917 DA180344 DA191279 DB505790 HQ258659 ADR83410 U10301 AAA67922 U10302 AAA67923 NM_000828 NP_000819 NM_001256743 NP_001243672 NM_007325 NP_015564 NM_181894
Function	Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. {ECO:0000269|PubMed:21172611}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=Interaction with CNIH2 and CNIH3 promotes cell surface expression. {ECO:0000250}.
Top Pathways	cAMP signaling pathway, Circadian entrainment, Retrograde endocannabinoid signaling, Nicotine addiction, Amphetamine addiction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Glutamate receptor 3 full length protein - ab132969 from Abcam Category Protein Source Wheat germ Species Human

Human Glutamate receptor 3 protein fragment - ab114562 from Abcam Category Protein Source Wheat germ Species Human

GRIA3 / GLUR3 Antibody Blocking Peptide - LS-E2916 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRIA3 / GLUR3 Antibody Blocking Peptide - LS-E12521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRIA3 / GLUR3 Antibody Blocking Peptide - LS-E12471 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Glutamate Receptor 3 Recombinant Protein - H00002892-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Glutamate Receptor 3 Protein - H00002892-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GRIA3-Antibody-N-term-Blocking-peptide - BP14041a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human GRIA3 protein - orb246744 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human GRIA3 protein - orb246353 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Glutamate receptor 3 / GLUR3 - H00002892-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Glutamate receptor 3 / GLUR3 - H00002892-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Glutamate receptor 3 / GLUR3 - H00002892-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Glutamate receptor 3 / GLUR3 - H00002892-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human GRIA3 - GRIA3-27524TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) - RPE803Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) - RPE803Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) - RPE803Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Glutamate Receptor, Metabotropic 3 (GRM3) - RPB891Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) - RPE803Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant human Glutamate receptor 3 - CSB-YP009900HU CSB-BP009900HU CSB-MP009900HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Glutamate receptor 3 - CSB-EP009900HU from Cusabio Category Protein Source E.coli Species Human

Glutamate Receptor 3 Recombinant Protein Antigen - NBP2-37972PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GRIA3 Peptide, Human - M34GP06648H from Creative Peptides Category Peptide Source Synthetic. Species Human

GRIA3 Recombinant Protein (OPCA01630) - OPCA01630 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

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