| Gene Symbol |
BIK
|
| Entrez Gene |
638
|
| Alt Symbol |
BIP1, BP4, NBK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BCL2-interacting killer (apoptosis-inducing)
|
| Other Description |
apoptosis inducer NBK|apoptosis-inducing NBK|bcl-2-interacting killer
|
| Swissprots |
Q13323 Q16582 Q6FH93
|
| Accessions |
AAF01156 AAO61089 CAA18260 EAW73282 EAW73283 EAW73284 Q13323 BC001599 AAH01599 BM765910 BP329261 BT006728 AAP35374 CR456390 CAG30276 CR541863 CAG46661 CR541883 CAG46681 CU012948 CAK54379 CU013236 CAK54678 DQ890578 ABM92195 DQ893738 ABM84664 DQ893745 ABM84671 U34584 AAC50413 U49730 AAC79124 NM_001197 NP_001188
|
| Function |
Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX. {ECO:0000269|PubMed:8521816}.
|
| Subcellular Location |
Endomembrane system; Single-pass membrane protein. Mitochondrion membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Around the nuclear envelope, and in cytoplasmic membranes.
|
