BIK

Gene Symbol BIK
Entrez Gene 638
Alt Symbol BIP1, BP4, NBK
Species Human
Gene Type protein-coding
Description BCL2-interacting killer (apoptosis-inducing)
Other Description apoptosis inducer NBK|apoptosis-inducing NBK|bcl-2-interacting killer
Swissprots Q13323 Q16582 Q6FH93
Accessions AAF01156 AAO61089 CAA18260 EAW73282 EAW73283 EAW73284 Q13323 BC001599 AAH01599 BM765910 BP329261 BT006728 AAP35374 CR456390 CAG30276 CR541863 CAG46661 CR541883 CAG46681 CU012948 CAK54379 CU013236 CAK54678 DQ890578 ABM92195 DQ893738 ABM84664 DQ893745 ABM84671 U34584 AAC50413 U49730 AAC79124 NM_001197 NP_001188
Function Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX. {ECO:0000269|PubMed:8521816}.
Subcellular Location Endomembrane system; Single-pass membrane protein. Mitochondrion membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Around the nuclear envelope, and in cytoplasmic membranes.

Bik Antibody - 4592 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Raji and Ramos cell lines using Bik Antibody.

NBK (FL-160) - sc-10770 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NBK (FL-160): sc-10770. Western blot analysis of NBK expression in Ramos (A) and HL-60 (B) whole cell lysates.

NBK (E-20) - sc-30552 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NBK (H-1) - sc-365625 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NBK (H-1): sc-365625. Western blot analysis of NBK expression in Ramos (A) and HL-60 (B) whole cell lysates.

NBK (G-20) - sc-30551 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NBK (N-19) - sc-1710 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NBK (N-19): sc-1710. Western blot analysis of NBK expression in BJAB whole cell lysate.

p-NBK (Thr 33) - sc-130206 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-NBK (Thr 33): sc-130206. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

Anti-Bik (phospho T33) antibody - ab55179 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bik (phospho T33) antibody (ab55179) at 1/500 dilutionLane 1 : extracts from HepG2 cells. Lane 2 : extracts from HepG2 cells, incubated with the immunising phosphopeptide.

Anti-Bik antibody - ab52182 from Abcam

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bik antibody (ab52182) at 1/500 dilutionLane 1 : extracts from A549 cells, treated with DMSO (0.1%, 10mins)Lane 2 : extracts from A549 cells, treated with DMSO (0.1%, 10mins) with blocking peptide

Anti-Bik antibody - ab54862 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Bik antibody (ab54862) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.

Anti-Bik antibody - ab41716 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Bik antibody - Aminoterminal end - ab62494 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Bik antibody - Aminoterminal end (ab62494) at 1 µg/mlLane 2 : Anti-Bik antibody - Aminoterminal end (ab62494) at 2 µg/mlLane 1 : Jurkat cell lysateLane 2 : Jurkat cell lysateLysates/proteins at 15 µg per lane.

Anti-BIK Antibody (N-Terminus) IHC-plus™ - LS-B454 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BIK antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B454 concentration 5 ug/ml.

Anti-BIK Antibody - LS-C146944 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (Internal) - LS-C210005 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (aa50-80, AP) - LS-C252559 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (aa50-80, APC) - LS-C252560 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (aa50-80, Biotin) - LS-C252561 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (aa50-80, FITC) - LS-C252562 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (aa50-80, Azide-free, HRP) - LS-C252563 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (aa50-80, PE) - LS-C252564 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (Thr33, AP) - LS-C275473 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody (aa18-67) - LS-C117549 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HUVEC cells, using BIK (Ab-33) Antibody. The picture on the right is treated with the synthesized peptide.

Anti-BIK Antibody (Thr33, Biotin) - LS-C275474 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BIK Antibody - LS-C148238 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed, paraffin-embedded tissue section of human kidney stained for Bik expression using LS-C148238 at 1:2000. A high level of Bik signal was seen in the distal collecting tubules, the glomeruli are primarily negative. Hematoxylin-Eosin counterstain.
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