Gene Symbol | EXTL3 |
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Entrez Gene | 2137 |
Alt Symbol | BOTV, EXTL1L, EXTR1, REGR, RPR |
Species | Human |
Gene Type | protein-coding |
Description | exostosin-like glycosyltransferase 3 |
Other Description | EXT-related 1|exostoses (multiple)-like 3|exostosin tumor-like 3|exostosin-like 3|glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|hereditary multiple exostoses gene isolog|putative tumor suppressor protein EXTL3|reg receptor |
Swissprots | D3DST8 Q53XT3 O00225 O43909 |
Accessions | AAB67602 EAW63507 EAW63508 EAW63509 O43909 AB007042 BAA24080 AB011091 BAA25445 AF001690 AAC39598 AF029231 AAD01877 AF083551 AAD42041 AK124619 AK294475 BAG57702 AW105691 BC006363 AAH06363 BI911162 BT007353 AAP36017 CR749646 CAH18440 DA222815 DA757362 DQ890698 ABM81624 DQ893883 ABM84809 U76188 AAB93670 XM_011544440 XP_011542742 NM_001440 NP_001431 NR_073468 NR_073469 |
Function | Probable glycosyltransferase (By similarity). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. {ECO:0000250, ECO:0000269|PubMed:22727489}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10639137}; Single-pass type II membrane protein {ECO:0000269|PubMed:10639137}. |
Tissue Specificity | Ubiquitous. Expressed in keratinocytes. {ECO:0000269|PubMed:22727489}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
EXTL3 (G-5) - sc-271986 from Santa Cruz Biotechnology
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EXTL3 (H-300) - sc-134991 from Santa Cruz Biotechnology
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EXTL3 (S-16) - sc-54268 from Santa Cruz Biotechnology
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Anti-EXTL3 antibody - ab113063 from Abcam
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Anti-EXTL3 antibody - ab94955 from Abcam
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Anti-EXTL3 Antibody (HRP) - LS-C211564 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (FITC) - LS-C211565 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (Biotin) - LS-C211566 from LifeSpan Bioscience
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Anti-EXTL3 Antibody - LS-C211560 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa50-80) - LS-C321237 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa750-919) - LS-C179082 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa345-374) - LS-C167868 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa43-72) - LS-C167869 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa345-374, AP) - LS-C256893 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa345-374, APC) - LS-C259303 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa345-374, PE) - LS-C259305 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (C-Terminus) - LS-C155373 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa43-72, AP) - LS-C259306 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa43-72, APC) - LS-C259308 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa43-72, PE) - LS-C259309 from LifeSpan Bioscience
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Anti-EXTL3 Antibody (aa352-382) - LS-C321233 from LifeSpan Bioscience
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Exostosin-like 3/EXTL3 Antibody - AF2635 from Novus Biologicals
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Exostosin-like 3/EXTL3 Antibody (311007) [Unconjugated] - MAB2635 from Novus Biologicals
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Exostosin-like 3/EXTL3 Antibody - NBP1-31645 from Novus Biologicals
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Exostosin-like 3/EXTL3 Antibody - NBP1-88378 from Novus Biologicals
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