Gene Symbol | EXTL3 |
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Entrez Gene | 2137 |
Alt Symbol | BOTV, EXTL1L, EXTR1, REGR, RPR |
Species | Human |
Gene Type | protein-coding |
Description | exostosin-like glycosyltransferase 3 |
Other Description | EXT-related 1|exostoses (multiple)-like 3|exostosin tumor-like 3|exostosin-like 3|glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|hereditary multiple exostoses gene isolog|putative tumor suppressor protein EXTL3|reg receptor |
Swissprots | D3DST8 Q53XT3 O00225 O43909 |
Accessions | AAB67602 EAW63507 EAW63508 EAW63509 O43909 AB007042 BAA24080 AB011091 BAA25445 AF001690 AAC39598 AF029231 AAD01877 AF083551 AAD42041 AK124619 AK294475 BAG57702 AW105691 BC006363 AAH06363 BI911162 BT007353 AAP36017 CR749646 CAH18440 DA222815 DA757362 DQ890698 ABM81624 DQ893883 ABM84809 U76188 AAB93670 XM_011544440 XP_011542742 NM_001440 NP_001431 NR_073468 NR_073469 |
Function | Probable glycosyltransferase (By similarity). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. {ECO:0000250, ECO:0000269|PubMed:22727489}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10639137}; Single-pass type II membrane protein {ECO:0000269|PubMed:10639137}. |
Tissue Specificity | Ubiquitous. Expressed in keratinocytes. {ECO:0000269|PubMed:22727489}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
Human EXTL3 protein fragment - ab127217 from Abcam
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EXTL3 Antibody Blocking Peptide - LS-E1899 from LifeSpan Bioscience
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EXTL3 Antibody Blocking Peptide - LS-E9915 from LifeSpan Bioscience
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Recombinant Human Exostosin-like 3/EXTL3 Protein - H00002137-P01 from Novus Biologicals
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EXTL3-Antibody-N-term-Blocking-peptide - BP12734a from Abgent, a WuXi AppTec company
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EXTL3-Antibody-N-term-Blocking-Peptide - BP9048a from Abgent, a WuXi AppTec company
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Recombinant human Exostosin-like 3 (OPCA00492) - OPCA00492 from Aviva Systems Biology
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Exostosin-like 3 - H00002137-P01-10 from Acris Antibodies
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Exostosin-like 3 - H00002137-P01-25 from Acris Antibodies
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EXTL3 fusion protein - Ag4473 from Proteintech Group
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EXTL3 fusion protein - ag0936 from Proteintech Group
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Recombinant Human EXTL3 Protein - BP002665-C342 from Syd Labs
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Recombinant Human EXTL3 - EXTL3-83H from Creative Biomart
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Recombinant human Exostosin-like 3 protein - CSB-EP030754h CSB-BP030754h CSB-MP030754h from Cusabio
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Recombinant human Exostosin-like 3 protein - CSB-RP030754h from Cusabio
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Recombinant Human Exostosin-like 3(EXTL3) ,partial - CSB-YP007905HU CSB-EP007905HU CSB-BP007905HU CSB-MP007905HU from Cusabio
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Exostosin-like 3 - RPC140516 from Biomatik
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Exostosin-like 3/EXTL3 Protein - NBP1-88378PEP from Novus Biologicals
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EXTL3 Peptide, Human - M34GP05155H from Creative Peptides
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Human EXTL3 protein - orb245163 from Biorbyt
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Exostosin-like 3, Recombinant Protein - MBS717253 from MyBioSource
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Exostosin-like 3 (EXTL3), partial, Recombinant Protein - MBS1084062 from MyBioSource
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Exostosin-like 3 protein - orb396056 from Biorbyt
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